Gait and mobility assessment in neurological conditions

Mobility, for example gait or physical activity characteristics, is a complex task that involves the integration and use of the central and peripheral nervous system, which makes it susceptible to neurological impairment due to disease or injury. This chapter provides an outline of mobility assessment in neurological conditions, such as Parkinson’s disease, Huntington’s disease, multiple sclerosis, dementia, stroke and traumatic brain injury. Discussion around the relevant mobility outcomes for different neurological conditions is provided, with reference to healthcare application and clinical trials. Recommendations and considerations for validation of technology, algorithms and outcomes in neurological conditions are provided, with specific reference to regulatory submissions for clinical trials. Overall, this chapter provides a brief overview of the complex arena of mobility measurement with digital health technologies in neurological conditions.