Habitual physical activity levels of adults with heart failure: systematic review and meta-analysis

Cara Jordan, Sarah J. Charman, Alan Mark Batterham, Darren Flynn, David Houghton, Linda Errington, Guy A. Macgowan, Leah Avery*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)
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Objective: To conduct a systematic review and meta-analysis to quantify habitual physical activity (PA) levels of patients with heart failure (HF) and assess the quality of reporting of device-assessed PA. Methods: Eight electronic databases were searched up to 17 November 2021. Data on the study and population characteristics, method of PA measurement and PA metrics were extracted. A random-effects meta-analysis (restricted maximum likelihood with Knapp-Hartung SE adjustment) was conducted. Results: Seventy-five studies were included in the review (n=7775 patients with HF). Meta-analysis was restricted to mean steps per day, encompassing 27 studies (n=1720 patients with HF). Pooled mean steps per day were 5040 (95% CI: 4272 to 5807). The 95% prediction interval for mean steps per day in a future study was 1262 to 8817. Meta-regression at the study level revealed that a 10-year increment in the mean age of patients was associated with 1121 fewer steps per day (95% CI: 258 to 1984). Conclusions: Patients with HF are a low-active population. These findings have implications for the way in which PA is targeted in patients with HF, and interventions should focus on addressing the age-related decline observed as well as increasing PA to improve HF symptoms and quality of life. PROSPERO registration number: CRD42020167786.
Original languageEnglish
Article numberheartjnl-2022-321943
Pages (from-to)1357-1362
Number of pages6
Issue number18
Early online date27 Feb 2023
Publication statusPublished - 1 Sept 2023

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