High-throughput computational methods and software for quantitative trait locus (QTL) mapping

2015

Cell Specific eQTL Analysis without Sorting Cells

Westra, H. J., Arends, D., Esko, T., Peters, M. J., Schurmann, C., Schramm, K., Kettunen, J., Yaghootkar, H., Fairfax, B. P., Andiappan, A. K., Li, Y., Fu, J., Karjalainen, J., Platteel, M., Visschedijk, M., Weersma, R. K., Kasela, S., Milani, L., Tserel, L. & Peterson, P. & 38 others, Reinmaa, E., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Homuth, G., Petersmann, A., Lorbeer, R., Prokisch, H., Meitinger, T., Herder, C., Roden, M., Grallert, H., Ripatti, S., Perola, M., Wood, A. R., Melzer, D., Ferrucci, L., Singleton, A. B., Hernandez, D. G., Knight, J. C., Melchiotti, R., Lee, B., Poidinger, M., Zolezzi, F., Larbi, A., Wang, D. Y., van den Berg, L. H., Veldink, J. H., Rotzschke, O., Makino, S., Salomaa, V., Strauch, K., Völker, U., van Meurs, J. B. J., Metspalu, A., Wijmenga, C., Jansen, R. C. & Franke, L., 8 May 2015, In: PLoS Genetics. 11, 5, 17 p., e1005223.

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81 Citations (Scopus)

15 Downloads (Pure)

Pheno2Geno - High-throughput generation of genetic markers and maps from molecular phenotypes for crosses between inbred strains

Zych, K., Li, Y., van der Velde, J. K., Joosen, R. V. L., Ligterink, W., Jansen, R. C. & Arends, D., 6 Feb 2015, In: BMC Bioinformatics. 16, 1, 51.

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Open Access

7 Citations (Scopus)

2014

WormQTL^HD - A web database for linking human disease to natural variation data in C. Elegans

Van Der Velde, K. J., De Haan, M., Zych, K., Arends, D., Snoek, L. B., Kammenga, J. E., Jansen, R. C., Swertz, M. A. & Li, Y., 1 Jan 2014, In: Nucleic Acids Research. 42, D1, p. D794-D801

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Open Access

16 Citations (Scopus)

2013

Identifying genotype-by-environment interactions in the metabolism of germinating arabidopsis seeds using generalized genetical genomics

Louis Joosen, R. V., Arends, D., Li, Y., Willems, L. A. J., Keurentjes, J. J. B., Ligterink, W., Jansen, R. C. & Hilhorst, H. W. M., Jun 2013, In: Plant Physiology. 162, 2, p. 553-566 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Citations (Scopus)

WormQTL-public archive and analysis web portal for natural variation data in Caenorhabditis spp

Snoek, L. B., Van Der Velde, K. J., Arends, D., Li, Y., Beyer, A., Elvin, M., Fisher, J., Hajnal, A., Hengartner, M. O., Poulin, G. B., Rodriguez, M., Schmid, T., Schrimpf, S., Xue, F., Jansen, R. C., Kammenga, J. E. & Swertz, M. A., 1 Jan 2013, In: Nucleic Acids Research. 41, D1, p. D738-D743

Research output: Contribution to journal › Article › peer-review

Open Access

27 Citations (Scopus)

2012

Visualizing the genetic landscape of Arabidopsis seed performance

Joosen, R. V. L., Arends, D., Willems, L. A. J., Ligterink, W., Jansen, R. C. & Hilhorst, H. W. M., Feb 2012, In: Plant Physiology. 158, 2, p. 570-589 20 p.

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Open Access

40 Citations (Scopus)

xQTL workbench: A scalable web environment for multi-level QTL analysis

Arends, D., van der Velde, K. J., Prins, P., Broman, K. W., Möller, S., Jansen, R. C. & Swertz, M. A., Apr 2012, In: Bioinformatics. 28, 7, p. 1042-1044 3 p., bts049.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Citations (Scopus)

2011

Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

Fehrmann, R. S. N., Jansen, R. C., Veldink, J. H., Westra, H.-J., Arends, D., Bonder, M. J., Fu, J., Deelen, P., Groen, H. J. M., Smolonska, A., Weersma, R. K., Hofstra, R. M. W., Buurman, W. A., Rensen, S., Wolfs, M. G. M., Platteel, M., Zhernakova, A., Elbers, C. C., Festen, E. M. & Trynka, G. & 8 others, Hofker, M. H., Saris, C. G. J., Ophoff, R. A., van den Berg, L. H., van Heel, D. A., Wijmenga, C., te Meerman, G. J. & Franke, L., 4 Aug 2011, In: PLoS Genetics. 7, 8, 14 p.

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274 Citations (Scopus)

2010

R/qtl: high-throughput multiple QTL mapping

Arends, D., Prins, P., Jansen, R. C. & Broman, K. W., 1 Oct 2010, In: Bioinformatics. 26, 23, p. 2990-2992 3 p.

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309 Citations (Scopus)

The MOLGENIS toolkit: Rapid prototyping of biosoftware at the push of a button

Swertz, M. A., Dijkstra, M., Adamusiak, T., van der Velde, J. K., Kanterakis, A., Roos, E. T., Lops, J., Thorisson, G. A., Arends, D., Byelas, G., Muilu, J., Brookes, A. J., De Brock, E. O., Jansen, R. C. & Parkinson, H., 21 Dec 2010, In: BMC Bioinformatics. 11, SUPPL. 12, S12.

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Open Access

92 Citations (Scopus)

XGAP: A uniform and extensible data model and software platform for genotype and phenotype experiments

Swertz, M. A., Velde, K. J. V. D., Tesson, B. M., Scheltema, R. A., Arends, D., Vera, G., Alberts, R., Dijkstra, M., Schofield, P., Schughart, K., Hancock, J. M., Smedley, D., Wolstencroft, K., Goble, C., de Brock, E. O., Jones, A. R., Parkinson, H. E. & Jansen, R. C., 9 Mar 2010, In: Genome Biology. 11, 3, r27.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Citations (Scopus)

High-throughput computational methods and software for quantitative trait locus (QTL) mapping

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