Inflammasome lights up in systemic sclerosis

John Henderson, Steven O'Reilly

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)
3 Downloads (Pure)


Systemic sclerosis (SSc) is a pro-fibrotic condition with a poorly understood aetiology. Evidence presented by Artlett et al. in this issue suggests that the microRNA miR-155 is key, with its involvement dependent on the NLRP3 inflammasome. This links epigenetic events with inflammasome signalling in SSc and opens the door to new therapeutic strategies for the treatment of SSc.
Original languageEnglish
Pages (from-to)205
JournalArthritis Research & Therapy
Issue number1
Publication statusPublished - 18 Sep 2017


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