The multipath transmission has been regarded as the most suitable transmission concept for high data rate packets such as video data. The video packets are split into different frames for transmission via different paths. The transmission is carried out concurrently, thus one path may interfere with another path. Considering the multipath video streaming, the issue of route coupling effect has been one of the major challenges of multipath transmission, especially in a vehicular network. The route coupling causes wireless contention and video packet collision. In this regard, this paper proposes a multipath video transmission protocol that considers path’s route coupling effect in order to minimize interference between multiple paths. The route coupling minimization strategy is based on selecting two dispersed vehicles based on an angle by the source vehicle within it network coverage. The link and node disjoint concepts are incorporated into the dispersed vehicle selection. In order to further ascertain vehicles with zero or low interference, the link signal power and bandwidth capability have been employed. Concerning the dispersed vehicle selection and link signal power, mathematical derivations are presented with their numerical analysis. In addition, performance evaluation of the proposed scheme has been performed based on the simulation carried out. The various results obtained from the simulation are benchmarked with the baseline research works. The results demonstrate that the proposed Interference-aware Multipath Solution with Link and Node Disjoint (IMSLND) protocol for video streaming offers higher video quality when compared to the baseline research works.