Mathematical modelling of glucose dynamics

Benoit Huard; Gemma Kirkham

doi:10.1016/j.coemr.2022.100379

Mathematical modelling of glucose dynamics

Benoit Huard^*, Gemma Kirkham

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

17 Citations (Scopus)

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Abstract

The accurate regulation of glucose within humans is an essential feature of homeostasis. It optimises energy release in the muscles and organs. Glucose rhythms driven by internal and external stimuli have been physiologically observed in humans and modelled mathematically to provide a solid framework for understanding these processes in a qualitative and quantitative manner. In this article, we review the latest contribution of mathematical modelling to the understanding and prediction of dynamics within the glucose regulation system.

Original language	English
Article number	100379
Journal	Current Opinion in Endocrine and Metabolic Research
Volume	25
Early online date	18 Jun 2022
DOIs	https://doi.org/10.1016/j.coemr.2022.100379
Publication status	Published - 1 Aug 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Diabetes
Differential equations
Glucagon
Glucose regulation
Insulin
Mathematical modelling

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10.1016/j.coemr.2022.100379Licence: CC BY

Huard_Kirkham_Glucose_review_June2022Accepted author manuscript, 1.05 MBLicence: CC BY

Cite this

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AU - Kirkham, Gemma

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AB - The accurate regulation of glucose within humans is an essential feature of homeostasis. It optimises energy release in the muscles and organs. Glucose rhythms driven by internal and external stimuli have been physiologically observed in humans and modelled mathematically to provide a solid framework for understanding these processes in a qualitative and quantitative manner. In this article, we review the latest contribution of mathematical modelling to the understanding and prediction of dynamics within the glucose regulation system.

KW - Diabetes

KW - Differential equations

KW - Glucagon

KW - Glucose regulation

KW - Insulin

KW - Mathematical modelling

UR - https://www.scopus.com/pages/publications/85136908420

U2 - 10.1016/j.coemr.2022.100379

DO - 10.1016/j.coemr.2022.100379

M3 - Review article

SN - 2451-9650

VL - 25

JO - Current Opinion in Endocrine and Metabolic Research

JF - Current Opinion in Endocrine and Metabolic Research

M1 - 100379

ER -

Mathematical modelling of glucose dynamics

Abstract

UN SDGs

Keywords

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