Objective: The purpose of this study was to quantify measurement error of 3-D kinematic and kinetic measures during overground endurance running between two sessions separated by 48 hours. Approach: 13 recreational runners were assessed on two occasions while running overground, over embedded force plates and through an array of 3-D cameras. Main results: In the sagittal, frontal and transverse planes, over the entire stance phase, the typical error of kinematic variables ranged from 1.33° – 6.16° for the hip, 1.38° – 6.01° for the knee and 0.48° – 7.36° for the ankle. Over the same time period and planes typical error of peak-joint moments ranged from 0.04 – 0.54 NmcenterdotKg-1 for the hip, 0.06 – 0.37 NmcenterdotKg-1 for the knee and 0.01 – 0.15 NmcenterdotKg-1 for the ankle. Significance: Results suggest 3-D kinematic and kinetic measures of the stance phase in overground-endurance running are reliable between sessions separated by 48 hours. The measurement error reported here could inform sample-size estimates for future studies and provide smallest-detectable changes for the interpretation of interventions performed over a similar time scale.