Mechanisms of neoplastic cell survival using melanoma as an example

Krystian Kasperowicz; Anna Gruszczyńska; Krzysztof Kowalik; Andrzej Modrzejewski

doi:10.5603/ocp.98830

Mechanisms of neoplastic cell survival using melanoma as an example

Krystian Kasperowicz, Anna Gruszczyńska, Krzysztof Kowalik^*, Andrzej Modrzejewski

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Abstract

We discuss various mechanisms of carcinogenesis using melanoma as an example. The article presents the cellular mechanism inducing pathological angiogenesis in neoplastic cells and the significance of the inflammatory process in carcinogenesis. A good understanding of the pathophysiology of tumors is key to creating new drugs and new forms of treatment. Exploring the mechanisms of tumor formation contributes to improving new therapies (new drugs, immunotherapy) and achieving higher survival rates in patients suffering from melanoma and other cancers. The article allows for a better understanding of the mechanisms of carcinogenesis.

Original language	English
Article number	#98830
Pages (from-to)	305-308
Number of pages	4
Journal	Oncology in Clinical Practice
Volume	21
Issue number	4
Early online date	21 Jun 2024
DOIs	https://doi.org/10.5603/ocp.98830
Publication status	Published - 13 Aug 2025
Externally published	Yes

Keywords

angiogenesis
melanoma
mutation
proliferative signals

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.5603/ocp.98830Licence: CC BY-NC-ND

98830-434826-2-PBFinal published version, 138 KBLicence: CC BY-NC-ND

Cite this

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title = "Mechanisms of neoplastic cell survival using melanoma as an example",

abstract = "We discuss various mechanisms of carcinogenesis using melanoma as an example. The article presents the cellular mechanism inducing pathological angiogenesis in neoplastic cells and the significance of the inflammatory process in carcinogenesis. A good understanding of the pathophysiology of tumors is key to creating new drugs and new forms of treatment. Exploring the mechanisms of tumor formation contributes to improving new therapies (new drugs, immunotherapy) and achieving higher survival rates in patients suffering from melanoma and other cancers. The article allows for a better understanding of the mechanisms of carcinogenesis.",

keywords = "angiogenesis, melanoma, mutation, proliferative signals",

author = "Krystian Kasperowicz and Anna Gruszczy{\'n}ska and Krzysztof Kowalik and Andrzej Modrzejewski",

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TY - JOUR

T1 - Mechanisms of neoplastic cell survival using melanoma as an example

AU - Kasperowicz, Krystian

AU - Gruszczyńska, Anna

AU - Kowalik, Krzysztof

AU - Modrzejewski, Andrzej

PY - 2025/8/13

Y1 - 2025/8/13

N2 - We discuss various mechanisms of carcinogenesis using melanoma as an example. The article presents the cellular mechanism inducing pathological angiogenesis in neoplastic cells and the significance of the inflammatory process in carcinogenesis. A good understanding of the pathophysiology of tumors is key to creating new drugs and new forms of treatment. Exploring the mechanisms of tumor formation contributes to improving new therapies (new drugs, immunotherapy) and achieving higher survival rates in patients suffering from melanoma and other cancers. The article allows for a better understanding of the mechanisms of carcinogenesis.

AB - We discuss various mechanisms of carcinogenesis using melanoma as an example. The article presents the cellular mechanism inducing pathological angiogenesis in neoplastic cells and the significance of the inflammatory process in carcinogenesis. A good understanding of the pathophysiology of tumors is key to creating new drugs and new forms of treatment. Exploring the mechanisms of tumor formation contributes to improving new therapies (new drugs, immunotherapy) and achieving higher survival rates in patients suffering from melanoma and other cancers. The article allows for a better understanding of the mechanisms of carcinogenesis.

KW - angiogenesis

KW - melanoma

KW - mutation

KW - proliferative signals

UR - https://www.scopus.com/pages/publications/105016352157

U2 - 10.5603/ocp.98830

DO - 10.5603/ocp.98830

M3 - Review article

AN - SCOPUS:105016352157

SN - 2450-1654

VL - 21

SP - 305

EP - 308

JO - Oncology in Clinical Practice

JF - Oncology in Clinical Practice

IS - 4

M1 - #98830

ER -

Mechanisms of neoplastic cell survival using melanoma as an example

Abstract

Keywords

UN SDGs

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