Metyrapone is an effective adjuvant treatment for major depression: Commentary

A.H. Young, J. Newham

Research output: Contribution to journalComment/debate


Patients: Sixty three people aged 18-75 years with a diagnosis of major depressive disorder (DSM-IV); a score of 18 or over on the Hamilton Rating Scale for Depression, 21 item version (HAMD-21); and free from antidepressant, antipsychotic, mood stabilising, and other medication for at least three days before the study began. CONCLUSIONS Addition of metyrapone to treatment with antidepressants improves symptoms of depression and accelerates the action of antidepressant drugs
Original languageEnglish
Pages (from-to)72-72
Number of pages1
JournalEvidence-Based Mental Health
Issue number3
Early online date25 Jul 2005
Publication statusPublished - 1 Aug 2005
Externally publishedYes


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