Modelling of tumour-induced angiogenesis with regress by immune factor

Wei Chen; Li Zhang; Ling Shao; Rosemary Bass; Chenyu Liu; Alamgir Hossain

doi:10.1109/SKIMA.2015.7399991

Modelling of tumour-induced angiogenesis with regress by immune factor

Wei Chen, Li Zhang, Ling Shao, Rosemary Bass, Chenyu Liu, Alamgir Hossain

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

An immune system is a collection of cells and molecules that can respond and generate resistance to disease, especially infectious disease. By enhancing a patient's immune system to augment conventional therapies is a clinical practice for long time. As there are a lot of clues that tumour can be influenced by immune system, in this paper we have developed a partial different equations (PDEs) model of tumour-induced angiogenesis with tumour cytotoxic immune factor delivered through the vessels formed. The model describes four variables, including endothelial cells (ECs), tumour, vessel and cytotoxic factor. The simulation results show that a big tumour can be regressed and recurred by the immune factor, and a small tumour can be eliminated completely by only enhancing the immune factor.

Original language	English
Title of host publication	Proceedings of the 9th International Conference on Software, Knowledge, Information Management and Applications (SKIMA 2015)
Place of Publication	Piscataway, NJ
Publisher	IEEE
Pages	1-8
ISBN (Print)	9781467367448
DOIs	https://doi.org/10.1109/SKIMA.2015.7399991
Publication status	Published - Dec 2015
Event	9th International Conference on Software, Knowledge, Information Management and Applications (SKIMA 2015) - Kathmandu Duration: 1 Dec 2015 → …

Conference

Conference	9th International Conference on Software, Knowledge, Information Management and Applications (SKIMA 2015)
Period	1/12/15 → …

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10.1109/SKIMA.2015.7399991

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title = "Modelling of tumour-induced angiogenesis with regress by immune factor",

abstract = "An immune system is a collection of cells and molecules that can respond and generate resistance to disease, especially infectious disease. By enhancing a patient's immune system to augment conventional therapies is a clinical practice for long time. As there are a lot of clues that tumour can be influenced by immune system, in this paper we have developed a partial different equations (PDEs) model of tumour-induced angiogenesis with tumour cytotoxic immune factor delivered through the vessels formed. The model describes four variables, including endothelial cells (ECs), tumour, vessel and cytotoxic factor. The simulation results show that a big tumour can be regressed and recurred by the immune factor, and a small tumour can be eliminated completely by only enhancing the immune factor.",

author = "Wei Chen and Li Zhang and Ling Shao and Rosemary Bass and Chenyu Liu and Alamgir Hossain",

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booktitle = "Proceedings of the 9th International Conference on Software, Knowledge, Information Management and Applications (SKIMA 2015)",

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Chen, W, Zhang, L, Shao, L, Bass, R, Liu, C & Hossain, A 2015, Modelling of tumour-induced angiogenesis with regress by immune factor. in Proceedings of the 9th International Conference on Software, Knowledge, Information Management and Applications (SKIMA 2015). IEEE, Piscataway, NJ, pp. 1-8, 9th International Conference on Software, Knowledge, Information Management and Applications (SKIMA 2015), 1/12/15. https://doi.org/10.1109/SKIMA.2015.7399991

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T1 - Modelling of tumour-induced angiogenesis with regress by immune factor

AU - Chen, Wei

AU - Zhang, Li

AU - Shao, Ling

AU - Bass, Rosemary

AU - Liu, Chenyu

AU - Hossain, Alamgir

PY - 2015/12

Y1 - 2015/12

N2 - An immune system is a collection of cells and molecules that can respond and generate resistance to disease, especially infectious disease. By enhancing a patient's immune system to augment conventional therapies is a clinical practice for long time. As there are a lot of clues that tumour can be influenced by immune system, in this paper we have developed a partial different equations (PDEs) model of tumour-induced angiogenesis with tumour cytotoxic immune factor delivered through the vessels formed. The model describes four variables, including endothelial cells (ECs), tumour, vessel and cytotoxic factor. The simulation results show that a big tumour can be regressed and recurred by the immune factor, and a small tumour can be eliminated completely by only enhancing the immune factor.

AB - An immune system is a collection of cells and molecules that can respond and generate resistance to disease, especially infectious disease. By enhancing a patient's immune system to augment conventional therapies is a clinical practice for long time. As there are a lot of clues that tumour can be influenced by immune system, in this paper we have developed a partial different equations (PDEs) model of tumour-induced angiogenesis with tumour cytotoxic immune factor delivered through the vessels formed. The model describes four variables, including endothelial cells (ECs), tumour, vessel and cytotoxic factor. The simulation results show that a big tumour can be regressed and recurred by the immune factor, and a small tumour can be eliminated completely by only enhancing the immune factor.

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DO - 10.1109/SKIMA.2015.7399991

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Y2 - 1 December 2015

ER -

Modelling of tumour-induced angiogenesis with regress by immune factor

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