Modelling of tumour-induced angiogenesis with regress by immune factor

Wei Chen, Li Zhang, Ling Shao, Rosemary Bass, Chenyu Liu, Alamgir Hossain

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

An immune system is a collection of cells and molecules that can respond and generate resistance to disease, especially infectious disease. By enhancing a patient's immune system to augment conventional therapies is a clinical practice for long time. As there are a lot of clues that tumour can be influenced by immune system, in this paper we have developed a partial different equations (PDEs) model of tumour-induced angiogenesis with tumour cytotoxic immune factor delivered through the vessels formed. The model describes four variables, including endothelial cells (ECs), tumour, vessel and cytotoxic factor. The simulation results show that a big tumour can be regressed and recurred by the immune factor, and a small tumour can be eliminated completely by only enhancing the immune factor.
Original languageEnglish
Title of host publicationProceedings of the 9th International Conference on Software, Knowledge, Information Management and Applications (SKIMA 2015)
Place of PublicationPiscataway, NJ
PublisherIEEE
Pages1-8
ISBN (Print)9781467367448
DOIs
Publication statusPublished - Dec 2015
Event9th International Conference on Software, Knowledge, Information Management and Applications (SKIMA 2015) - Kathmandu
Duration: 1 Dec 2015 → …

Conference

Conference9th International Conference on Software, Knowledge, Information Management and Applications (SKIMA 2015)
Period1/12/15 → …

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