Multi-Population Differential Evolution for Retinal Blood Vessel Segmentation

The retinal blood vessel segmentation plays a significant role in the automatic or computer-assisted diagnosis of retinopathy. Manual blood vessel segmentation is very time consuming and requires a great amount of domain knowledge. In addition, the blood vessels are only a few pixels wide and cover the entire fundus image. This further hinders the recent systems from automating the retinal blood vessel segmentation efficiently. In this paper, we propose a modified differential evolution (DE) algorithm to carry out automatic retinal blood vessel segmentation. The modified DE employs cross-communication among multiple populations to select three types of features i.e. thick blood vessels, thin blood vessels and non-blood vessels. Multiple classifiers such as neural networks (NN), Support vector machines (SVM), NN based and SVM based ensembles are used to further measure the performance of segmentation. The proposed algorithm is evaluated on three publicly available retinal image datasets like DRIVE, STARE and HRF. It outperformed the state-of-the-art with a high average accuracy of 98.5% along with high sensitivity and specificity.