Neuropsychiatric sequelae of early nutritional modifications: A beginner’s guide to behavioral analysis

Ann Katrin Kraeuter, Paul C. Guest, Zoltán Sarnyai

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

Early parental nutritional interventions during prenatal development have been shown to result in neuropsychiatric sequelae in the adult offspring. In order to understand the impact of such nutritional interventions, the behavior of the animal has to be carefully analyzed. This chapter provides a step-by-step guide to conduct behavioral tests in adult mice for investigators without specific expertise or those without the equipment to carry out behavioral studies. We focus on tests tapping into the main behavioral abnormalities that correspond to mental illnesses. We describe the materials required and the detailed methods to conduct global assessment of parameters such as behavioral integrity and general well-being, psychomotor activity, social behavior, repetitive behavior, anxiety-like behavior, depression-like behavior, short-term spatial working memory, and spatial reference memory.
Original languageEnglish
Title of host publicationInvestigations of Early Nutrition Effects on Long-Term Health
Subtitle of host publicationMethods and Applications
EditorsPaul C. Guest
Place of PublicationNew York
PublisherHumana Press Inc.
Chapter28
Pages403-420
Number of pages18
ISBN (Electronic)9781493976140
ISBN (Print)9781493976133
DOIs
Publication statusPublished - 30 Jan 2018
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume1735

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