Neuropsychological assessment of current and past crack cocaine users

Lúcio Garcia De Oliveira, Lcia Pereira Barroso, Camila Magalhães Silveira, Zila Van Der Meer Sanchez, Julio De Carvalho Ponce, Leonardo José Vaz, Solange Aparecida Nappo

Research output: Contribution to journalArticlepeer-review

51 Citations (Scopus)


Background: Cognitive changes due to crack cocaine consumption remain unclear. Methods: For clarification, 55 subjects were assigned to three groups: control group, crack cocaine current users, and ex-users. Participants were submitted to Mini-Mental State Examination (MMSE) and tasks evaluating executive functioning and verbal memory. Mood state was also measured. Intergroup comparisons were carried out. Results: Control group performance on the MMSE was better than that of users and ex-users. Verbal memory performance for logical memory of users was impaired. Ex-users scored lower on DSST and Trail Making Test (Part B). Conclusion: Chronic crack cocaine use seems to disrupt general cognitive functioning (MMSE), verbal memory, and attentional resources, but findings suggest that some of these effects could be reversed by abstinence.

Original languageEnglish
Pages (from-to)1941-1957
Number of pages17
JournalSubstance Use and Misuse
Issue number13
Early online date9 Dec 2009
Publication statusPublished - 16 Dec 2009
Externally publishedYes

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