Neuropsychological assessment of current and past crack cocaine users

Lúcio Garcia De Oliveira; Lcia Pereira Barroso; Camila Magalhães Silveira; Zila Van Der Meer Sanchez; Julio De Carvalho Ponce; Leonardo José Vaz; Solange Aparecida Nappo

doi:10.3109/10826080902848897

Neuropsychological assessment of current and past crack cocaine users

Lúcio Garcia De Oliveira, Lcia Pereira Barroso, Camila Magalhães Silveira, Zila Van Der Meer Sanchez, Julio De Carvalho Ponce, Leonardo José Vaz, Solange Aparecida Nappo

Research output: Contribution to journal › Article › peer-review

51 Citations (Scopus)

Abstract

Background: Cognitive changes due to crack cocaine consumption remain unclear. Methods: For clarification, 55 subjects were assigned to three groups: control group, crack cocaine current users, and ex-users. Participants were submitted to Mini-Mental State Examination (MMSE) and tasks evaluating executive functioning and verbal memory. Mood state was also measured. Intergroup comparisons were carried out. Results: Control group performance on the MMSE was better than that of users and ex-users. Verbal memory performance for logical memory of users was impaired. Ex-users scored lower on DSST and Trail Making Test (Part B). Conclusion: Chronic crack cocaine use seems to disrupt general cognitive functioning (MMSE), verbal memory, and attentional resources, but findings suggest that some of these effects could be reversed by abstinence.

Original language	English
Pages (from-to)	1941-1957
Number of pages	17
Journal	Substance Use and Misuse
Volume	44
Issue number	13
Early online date	9 Dec 2009
DOIs	https://doi.org/10.3109/10826080902848897
Publication status	Published - 16 Dec 2009
Externally published	Yes

Keywords

Abstinence
Cocaine
Cognition
Crack cocaine
Drugs
Memory
Neuropsychology

Access to Document

10.3109/10826080902848897

Cite this

@article{10af565aeb5946898dfab4b67b6ee98d,

title = "Neuropsychological assessment of current and past crack cocaine users",

abstract = "Background: Cognitive changes due to crack cocaine consumption remain unclear. Methods: For clarification, 55 subjects were assigned to three groups: control group, crack cocaine current users, and ex-users. Participants were submitted to Mini-Mental State Examination (MMSE) and tasks evaluating executive functioning and verbal memory. Mood state was also measured. Intergroup comparisons were carried out. Results: Control group performance on the MMSE was better than that of users and ex-users. Verbal memory performance for logical memory of users was impaired. Ex-users scored lower on DSST and Trail Making Test (Part B). Conclusion: Chronic crack cocaine use seems to disrupt general cognitive functioning (MMSE), verbal memory, and attentional resources, but findings suggest that some of these effects could be reversed by abstinence.",

keywords = "Abstinence, Cocaine, Cognition, Crack cocaine, Drugs, Memory, Neuropsychology",

author = "{De Oliveira}, {L{\'u}cio Garcia} and Barroso, {Lcia Pereira} and Silveira, {Camila Magalh{\~a}es} and {Van Der Meer Sanchez}, Zila and {De Carvalho Ponce}, Julio and Vaz, {Leonardo Jos{\'e}} and Nappo, {Solange Aparecida}",

year = "2009",

month = dec,

day = "16",

doi = "10.3109/10826080902848897",

language = "English",

volume = "44",

pages = "1941--1957",

journal = "Substance Use and Misuse",

issn = "1082-6084",

publisher = "Informa Healthcare",

number = "13",

}

TY - JOUR

T1 - Neuropsychological assessment of current and past crack cocaine users

AU - De Oliveira, Lúcio Garcia

AU - Barroso, Lcia Pereira

AU - Silveira, Camila Magalhães

AU - Van Der Meer Sanchez, Zila

AU - De Carvalho Ponce, Julio

AU - Vaz, Leonardo José

AU - Nappo, Solange Aparecida

PY - 2009/12/16

Y1 - 2009/12/16

N2 - Background: Cognitive changes due to crack cocaine consumption remain unclear. Methods: For clarification, 55 subjects were assigned to three groups: control group, crack cocaine current users, and ex-users. Participants were submitted to Mini-Mental State Examination (MMSE) and tasks evaluating executive functioning and verbal memory. Mood state was also measured. Intergroup comparisons were carried out. Results: Control group performance on the MMSE was better than that of users and ex-users. Verbal memory performance for logical memory of users was impaired. Ex-users scored lower on DSST and Trail Making Test (Part B). Conclusion: Chronic crack cocaine use seems to disrupt general cognitive functioning (MMSE), verbal memory, and attentional resources, but findings suggest that some of these effects could be reversed by abstinence.

AB - Background: Cognitive changes due to crack cocaine consumption remain unclear. Methods: For clarification, 55 subjects were assigned to three groups: control group, crack cocaine current users, and ex-users. Participants were submitted to Mini-Mental State Examination (MMSE) and tasks evaluating executive functioning and verbal memory. Mood state was also measured. Intergroup comparisons were carried out. Results: Control group performance on the MMSE was better than that of users and ex-users. Verbal memory performance for logical memory of users was impaired. Ex-users scored lower on DSST and Trail Making Test (Part B). Conclusion: Chronic crack cocaine use seems to disrupt general cognitive functioning (MMSE), verbal memory, and attentional resources, but findings suggest that some of these effects could be reversed by abstinence.

KW - Abstinence

KW - Cocaine

KW - Cognition

KW - Crack cocaine

KW - Drugs

KW - Memory

KW - Neuropsychology

UR - http://www.scopus.com/inward/record.url?scp=72849122804&partnerID=8YFLogxK

U2 - 10.3109/10826080902848897

DO - 10.3109/10826080902848897

M3 - Article

C2 - 20001290

AN - SCOPUS:72849122804

SN - 1082-6084

VL - 44

SP - 1941

EP - 1957

JO - Substance Use and Misuse

JF - Substance Use and Misuse

IS - 13

ER -

Neuropsychological assessment of current and past crack cocaine users

Abstract

Keywords

Access to Document

Other files and links

Cite this