Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumor immunity

Kai S. Lipinski; Stephen Todryk; Andrew Mountain; Steven Pelech; Alistair S. Irvine; Robert Kraaij; Chris Bangma; Kingston H. G. Mills

doi:10.1007/s00262-005-0014-9

Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumor immunity

Kai S. Lipinski, Stephen Todryk, Andrew Mountain, Steven Pelech, Alistair S. Irvine, Robert Kraaij, Chris Bangma, Kingston H. G. Mills

Applied Sciences Department

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Original language	English
Pages (from-to)	347-354
Journal	Cancer Immunology Immunotherapy
Volume	55
Issue number	3
DOIs	https://doi.org/10.1007/s00262-005-0014-9
Publication status	Published - Mar 2006

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10.1007/s00262-005-0014-9

Cite this

@article{998c5bb1321d4c899bf02503e331b4d4,

title = "Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumor immunity",

author = "Lipinski, {Kai S.} and Stephen Todryk and Andrew Mountain and Steven Pelech and Irvine, {Alistair S.} and Robert Kraaij and Chris Bangma and Mills, {Kingston H. G.}",

note = "Supervisor investigating immunotherapy of tumours. Funded by Science Foundation Ireland in collaboration with Trinity College Dublin, ML Research (Biotech) and Kinexus Bioinformatics Corp., Canada. The study showed that killing tumour cells by “suicide gene therapy” induces stress proteins that increase anti-tumour immune responses and reduce or inhibit tumour growth in-vivo.",

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month = mar,

doi = "10.1007/s00262-005-0014-9",

language = "English",

volume = "55",

pages = "347--354",

journal = "Cancer Immunology Immunotherapy",

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T1 - Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumor immunity

AU - Lipinski, Kai S.

AU - Todryk, Stephen

AU - Mountain, Andrew

AU - Pelech, Steven

AU - Irvine, Alistair S.

AU - Kraaij, Robert

AU - Bangma, Chris

AU - Mills, Kingston H. G.

N1 - Supervisor investigating immunotherapy of tumours. Funded by Science Foundation Ireland in collaboration with Trinity College Dublin, ML Research (Biotech) and Kinexus Bioinformatics Corp., Canada. The study showed that killing tumour cells by “suicide gene therapy” induces stress proteins that increase anti-tumour immune responses and reduce or inhibit tumour growth in-vivo.

PY - 2006/3

Y1 - 2006/3

U2 - 10.1007/s00262-005-0014-9

DO - 10.1007/s00262-005-0014-9

M3 - Article

SN - 0340-7004

SN - 1432-0851

VL - 55

SP - 347

EP - 354

JO - Cancer Immunology Immunotherapy

JF - Cancer Immunology Immunotherapy

IS - 3

ER -