Novel Variant and Known Mutation in 23S rRNA Gene of Mycoplasma pneumoniae, Northern Vietnam, 2023

Dinh Dung Nguyen; Nhan Thi Ho; Lynn G. Dover; Anh Hang Mai Vo; Ha Thi Thanh Ly; Phuong Mai Doan; Hang Thi Nguyen; Nguyen Thi Thao Luu; An Nhat Pham; Huyen Thi Thanh Tran

doi:10.3201/eid3005.231632

Novel Variant and Known Mutation in 23S rRNA Gene of Mycoplasma pneumoniae, Northern Vietnam, 2023

Dinh Dung Nguyen, Nhan Thi Ho, Lynn G. Dover, Anh Hang Mai Vo, Ha Thi Thanh Ly, Phuong Mai Doan, Hang Thi Nguyen, Nguyen Thi Thao Luu, An Nhat Pham, Huyen Thi Thanh Tran^*

^*Corresponding author for this work

Applied Sciences Department

Research output: Contribution to journal › Letter › peer-review

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Abstract

During a 2023 outbreak of Mycoplasma pneumoniae–associated community-acquired pneumonia among children in northern Vietnam, we analyzed M. pneumoniae isolated from nasopharyngeal samples. In almost half (6 of 13) of samples tested, we found known A2063G mutations (macrolide resistance) and a novel C2353T variant on the 23S rRNA gene.

Original language	English
Pages (from-to)	1034-1036
Number of pages	3
Journal	Emerging Infectious Diseases
Volume	30
Issue number	5
Early online date	4 Apr 2024
DOIs	https://doi.org/10.3201/eid3005.231632
Publication status	Published - 1 May 2024

Keywords

Mycoplasma pneumoniae
macrolide-resistant mutation
C2353T
A2063G
bacteria
community-acquired pneumonia
Vietnam

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3201/eid3005.231632

EID-23-1632.R2_AAMAccepted author manuscript, 1.51 MB
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Cite this

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title = "Novel Variant and Known Mutation in 23S rRNA Gene of Mycoplasma pneumoniae, Northern Vietnam, 2023",

abstract = "During a 2023 outbreak of Mycoplasma pneumoniae–associated community-acquired pneumonia among children in northern Vietnam, we analyzed M. pneumoniae isolated from nasopharyngeal samples. In almost half (6 of 13) of samples tested, we found known A2063G mutations (macrolide resistance) and a novel C2353T variant on the 23S rRNA gene.",

keywords = "Mycoplasma pneumoniae, macrolide-resistant mutation, C2353T, A2063G, bacteria, community-acquired pneumonia, Vietnam",

author = "Nguyen, {Dinh Dung} and Ho, {Nhan Thi} and Dover, {Lynn G.} and {Mai Vo}, {Anh Hang} and {Thanh Ly}, {Ha Thi} and {Mai Doan}, Phuong and {Thi Nguyen}, Hang and {Thao Luu}, {Nguyen Thi} and Pham, {An Nhat} and {Thanh Tran}, {Huyen Thi}",

year = "2024",

month = may,

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doi = "10.3201/eid3005.231632",

language = "English",

volume = "30",

pages = "1034--1036",

journal = "Emerging Infectious Diseases",

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TY - JOUR

T1 - Novel Variant and Known Mutation in 23S rRNA Gene of Mycoplasma pneumoniae, Northern Vietnam, 2023

AU - Nguyen, Dinh Dung

AU - Ho, Nhan Thi

AU - Dover, Lynn G.

AU - Mai Vo, Anh Hang

AU - Thanh Ly, Ha Thi

AU - Mai Doan, Phuong

AU - Thi Nguyen, Hang

AU - Thao Luu, Nguyen Thi

AU - Pham, An Nhat

AU - Thanh Tran, Huyen Thi

PY - 2024/5/1

Y1 - 2024/5/1

N2 - During a 2023 outbreak of Mycoplasma pneumoniae–associated community-acquired pneumonia among children in northern Vietnam, we analyzed M. pneumoniae isolated from nasopharyngeal samples. In almost half (6 of 13) of samples tested, we found known A2063G mutations (macrolide resistance) and a novel C2353T variant on the 23S rRNA gene.

AB - During a 2023 outbreak of Mycoplasma pneumoniae–associated community-acquired pneumonia among children in northern Vietnam, we analyzed M. pneumoniae isolated from nasopharyngeal samples. In almost half (6 of 13) of samples tested, we found known A2063G mutations (macrolide resistance) and a novel C2353T variant on the 23S rRNA gene.

KW - Mycoplasma pneumoniae

KW - macrolide-resistant mutation

KW - C2353T

KW - A2063G

KW - bacteria

KW - community-acquired pneumonia

KW - Vietnam

UR - http://www.scopus.com/inward/record.url?scp=85191614800&partnerID=8YFLogxK

U2 - 10.3201/eid3005.231632

DO - 10.3201/eid3005.231632

M3 - Letter

C2 - 38573165

AN - SCOPUS:85191614800

SN - 1080-6040

VL - 30

SP - 1034

EP - 1036

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 5

ER -

Novel Variant and Known Mutation in 23S rRNA Gene of Mycoplasma pneumoniae, Northern Vietnam, 2023

Abstract

Keywords

UN SDGs

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