Pathways of Corneal and Ocular Surface Inflammation: A Perspective from the Cullen Symposium

Alison McDermott, Victor Perez, Andrew Huang, Stephen Pflugfelder, Michael Stern, Christophe Baudouin, Roger Beuerman, Alan Burns, Virginia Calder, Margarita Calonge, James Chodosh, Douglas Coster, Reza Dana, Linda Hazlett, Dan Jones, Stella Kim, Erich Knop, De-Quan Li, Bradley Mitchell, Jerry NiederkornEric Pearlman, Kirk Wilhelmus, Elaine Kurie

Research output: Contribution to journalArticlepeer-review

53 Citations (Scopus)

Abstract

The goal of this symposium was to coalesce information presented by 22 investigators in the field of corneal and ocular surface inflammation into common pathways of inflammation. The perspective elucidated in this article defines the components of the normal ocular surface immune architecture and describes the consensus reached on the mechanisms/pathways involved in 1) acute inflammation; 2) late-stage (chronic) response; and 3) allergic disease. Seven diagrams didactically illustrate mechanisms. This paper is the introductory article in a supplement containing 18 articles by the symposium participants.
Original languageEnglish
Pages (from-to)S131-S138
JournalThe Ocular Surface
Volume3
Issue number4
DOIs
Publication statusPublished - Oct 2005

Keywords

  • Allergy
  • amplifying factors
  • cell mediators
  • conjunctival-associated lymphoid tissue
  • Cullen Symposium on Corneal and Ocular Surface Inflammation
  • inflammation
  • ocular surface inflammation
  • signaling pathways

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