TY - JOUR
T1 - Peak expiratory flow mediates the relationship between handgrip strength and timed up and go performance in elderly women, but not men
AU - Ritti-Dias, Raphael Mendes
AU - Cucato, Gabriel Grizzo
AU - de Mello Franco, Fábio Gazelato
AU - Cendoroglo, Maysa Seabra
AU - Nasri, Fábio
AU - Monteiro-Costa, Maria Luiza
AU - de Carvalho, José Antonio Maluf
AU - de Matos, Luciana Diniz Nagem Janot
PY - 2016/9
Y1 - 2016/9
N2 - OBJECTIVE: The aim of the present study was to verify if there is sex difference in the associations among handgrip strength, peak expiratory flow (PEF) and timed up and go (TUG) test results.METHODS: The sample included 288 consecutive elderly men (n=93) and women (n=195). Functional capacity was measured using the TUG test, and muscle strength was measured based on handgrip. Moreover, as a measure of current health status, PEF was evaluated. Linear regression procedures were performed to analyze the relationships between handgrip and both PEF and TUG test results, with adjustment for confounders, and to identify the possible mediating role of PEF in the association between handgrip strength and TUG test results.RESULTS: In men, handgrip strength was associated with both PEF and TUG performance (p<0.01). After adjustment for PEF, the relationship between handgrip strength and TUG performance remained significant. In women, handgrip strength was also associated with both PEF and TUG performance (p<0.01). However, after adjustment for PEF, the relationship between handgrip strength and TUG performance was no longer significant.CONCLUSION: Mobility in the elderly is sex dependent. In particular, PEF mediates the relationship between handgrip strength and TUG performance in women, but not in men.
AB - OBJECTIVE: The aim of the present study was to verify if there is sex difference in the associations among handgrip strength, peak expiratory flow (PEF) and timed up and go (TUG) test results.METHODS: The sample included 288 consecutive elderly men (n=93) and women (n=195). Functional capacity was measured using the TUG test, and muscle strength was measured based on handgrip. Moreover, as a measure of current health status, PEF was evaluated. Linear regression procedures were performed to analyze the relationships between handgrip and both PEF and TUG test results, with adjustment for confounders, and to identify the possible mediating role of PEF in the association between handgrip strength and TUG test results.RESULTS: In men, handgrip strength was associated with both PEF and TUG performance (p<0.01). After adjustment for PEF, the relationship between handgrip strength and TUG performance remained significant. In women, handgrip strength was also associated with both PEF and TUG performance (p<0.01). However, after adjustment for PEF, the relationship between handgrip strength and TUG performance was no longer significant.CONCLUSION: Mobility in the elderly is sex dependent. In particular, PEF mediates the relationship between handgrip strength and TUG performance in women, but not in men.
KW - Activities of Daily Living
KW - Aged
KW - Aged, 80 and over
KW - Aging/physiology
KW - Cross-Sectional Studies
KW - Female
KW - Geriatric Assessment/methods
KW - Hand Strength/physiology
KW - Humans
KW - Linear Models
KW - Locomotion/physiology
KW - Male
KW - Peak Expiratory Flow Rate/physiology
KW - Sex Factors
KW - Time Factors
KW - Time and Motion Studies
U2 - 10.6061/clinics/2016(09)06
DO - 10.6061/clinics/2016(09)06
M3 - Article
C2 - 27652833
VL - 71
SP - 517
EP - 520
JO - Clinics
JF - Clinics
SN - 1807-5932
IS - 9
ER -