Profile of neuropsychological deficits in older stroke survivors without dementia

Clive Ballard; Sally Stephens; Rose Anne Kenny; Raj Kalaria; Martin Tovee; John O'Brien

doi:10.1159/000069994

Profile of neuropsychological deficits in older stroke survivors without dementia

Clive Ballard^*, Sally Stephens, Rose Anne Kenny, Raj Kalaria, Martin Tovee, John O'Brien

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

82 Citations (Scopus)

Abstract

Background: Few studies have examined the profile of cognitive impairments in older stroke patients without dementia. Method: A standardized evaluation including a detailed neuropsychological assessment [Cambridge Examination for Mental Disorders in the Elderly - cognitive subscale (CAMCOG)] and computerised tests of attention and working memory from the Cognitive Drug Research battery were undertaken in 150 stroke survivors of >75 years of age and 30 elderly controls. Results: The stroke survivors without dementia had significantly greater overall impairment on the CAMCOG, as well as significantly greater impairment in memory, simple reaction time, choice reaction time (CRT), vigilance accuracy, CRT variability, spatial working memory reaction time (SWMRT) and numerical working memory than the elderly controls (e.g. CRT ↑ 33%, SWMRT ↑ 61%, memory ↓ 11%). Conclusion: Impairments of cognitive processing speed, working memory and executive functions are frequent in elderly stroke patients without dementia and represent the main cognitive components of early cognitive impairments.

Original language	English
Pages (from-to)	52-56
Number of pages	5
Journal	Dementia and Geriatric Cognitive Disorders
Volume	16
Issue number	1
DOIs	https://doi.org/10.1159/000069994
Publication status	Published - 1 May 2003
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1159/000069994

Cite this

@article{ab4e1f9c5ebe4cacbb7a6a55809e06f4,

title = "Profile of neuropsychological deficits in older stroke survivors without dementia",

abstract = "Background: Few studies have examined the profile of cognitive impairments in older stroke patients without dementia. Method: A standardized evaluation including a detailed neuropsychological assessment [Cambridge Examination for Mental Disorders in the Elderly - cognitive subscale (CAMCOG)] and computerised tests of attention and working memory from the Cognitive Drug Research battery were undertaken in 150 stroke survivors of >75 years of age and 30 elderly controls. Results: The stroke survivors without dementia had significantly greater overall impairment on the CAMCOG, as well as significantly greater impairment in memory, simple reaction time, choice reaction time (CRT), vigilance accuracy, CRT variability, spatial working memory reaction time (SWMRT) and numerical working memory than the elderly controls (e.g. CRT ↑ 33%, SWMRT ↑ 61%, memory ↓ 11%). Conclusion: Impairments of cognitive processing speed, working memory and executive functions are frequent in elderly stroke patients without dementia and represent the main cognitive components of early cognitive impairments.",

keywords = "Cognition, Neuropsychological deficit, Stroke",

author = "Clive Ballard and Sally Stephens and Kenny, {Rose Anne} and Raj Kalaria and Martin Tovee and John O'Brien",

year = "2003",

month = may,

day = "1",

doi = "10.1159/000069994",

language = "English",

volume = "16",

pages = "52--56",

journal = "Dementia and Geriatric Cognitive Disorders",

issn = "1420-8008",

publisher = "S. Karger AG",

number = "1",

}

TY - JOUR

T1 - Profile of neuropsychological deficits in older stroke survivors without dementia

AU - Ballard, Clive

AU - Stephens, Sally

AU - Kenny, Rose Anne

AU - Kalaria, Raj

AU - Tovee, Martin

AU - O'Brien, John

PY - 2003/5/1

Y1 - 2003/5/1

N2 - Background: Few studies have examined the profile of cognitive impairments in older stroke patients without dementia. Method: A standardized evaluation including a detailed neuropsychological assessment [Cambridge Examination for Mental Disorders in the Elderly - cognitive subscale (CAMCOG)] and computerised tests of attention and working memory from the Cognitive Drug Research battery were undertaken in 150 stroke survivors of >75 years of age and 30 elderly controls. Results: The stroke survivors without dementia had significantly greater overall impairment on the CAMCOG, as well as significantly greater impairment in memory, simple reaction time, choice reaction time (CRT), vigilance accuracy, CRT variability, spatial working memory reaction time (SWMRT) and numerical working memory than the elderly controls (e.g. CRT ↑ 33%, SWMRT ↑ 61%, memory ↓ 11%). Conclusion: Impairments of cognitive processing speed, working memory and executive functions are frequent in elderly stroke patients without dementia and represent the main cognitive components of early cognitive impairments.

AB - Background: Few studies have examined the profile of cognitive impairments in older stroke patients without dementia. Method: A standardized evaluation including a detailed neuropsychological assessment [Cambridge Examination for Mental Disorders in the Elderly - cognitive subscale (CAMCOG)] and computerised tests of attention and working memory from the Cognitive Drug Research battery were undertaken in 150 stroke survivors of >75 years of age and 30 elderly controls. Results: The stroke survivors without dementia had significantly greater overall impairment on the CAMCOG, as well as significantly greater impairment in memory, simple reaction time, choice reaction time (CRT), vigilance accuracy, CRT variability, spatial working memory reaction time (SWMRT) and numerical working memory than the elderly controls (e.g. CRT ↑ 33%, SWMRT ↑ 61%, memory ↓ 11%). Conclusion: Impairments of cognitive processing speed, working memory and executive functions are frequent in elderly stroke patients without dementia and represent the main cognitive components of early cognitive impairments.

KW - Cognition

KW - Neuropsychological deficit

KW - Stroke

UR - http://www.scopus.com/inward/record.url?scp=0037269770&partnerID=8YFLogxK

U2 - 10.1159/000069994

DO - 10.1159/000069994

M3 - Article

C2 - 12714801

AN - SCOPUS:0037269770

VL - 16

SP - 52

EP - 56

JO - Dementia and Geriatric Cognitive Disorders

JF - Dementia and Geriatric Cognitive Disorders

SN - 1420-8008

IS - 1

ER -

Profile of neuropsychological deficits in older stroke survivors without dementia

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this