Pulse mode operation of Love wave devices for biosensing applications

Michael Newton, Glen McHale, Fabrice Martin, Electra Gizeli, Kathryn Melzak

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

In this work we present a novel pulse mode Love wave biosensor that monitors both changes in amplitude and phase. A series of concentrations of 3350 molecular weight poly(ethylene glycol) (PEG) solutions are used as a calibration sequence for the pulse mode system using a network analyzer and high frequency oscilloscope. The operation of the pulse mode system is then compared to the continuous wave network analyzer by showing a sequence of deposition and removal of a model mass layer of palmitoyl-oleoyl-sn-glycerophosphocholine (POPC) vesicles. This experimental apparatus has the potential for making many hundreds of measurements a minute and so allowing the dynamics of fast interactions to be observed.
Original languageEnglish
Pages (from-to)2107-2109
Number of pages3
JournalAnalyst
Volume126
Issue number12
DOIs
Publication statusPublished - 16 Nov 2001

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