Qualitative evaluation of a weight loss intervention using total diet replacement (TDR) for diabetes reversal in the Diabetes REmission Clinical Trial (DiRECT)

Lucia Rehackova, Angela M Rodrigues , Naomi Brosnahan, Alison C Barnes, Sviatlana Zhyzhneuskaya, Carl Peters, Michael E.J. Lean, Ashley Adamson, Roy Taylor, Falko Sniehotta

Research output: Contribution to journalConference article

Abstract

Aims:To provide a qualitative evaluation of a 12-week TDR stage of the DiRECT intervention delivered in UK primary care,aiming to reverse Type 2 diabetes.
Methods:Participants matched for gender and socioeconomic status across trial sites were interviewed at baseline (T1), six weeks into the TDR (T2) and two weeks after food reintroduction (FR)(T3). The interviews were semi-structured, audio-recorded, transcribed verbatim and analysed using the framework approach.
Results: Out of 34 intervention participants interviewed at T1, 27 were available for a follow-up at T2 and 25 were available at T3. Eight participants withdrew from the study during the TDR. Narratives of 21 participants with complete data were analysed. Desiring normality in the form of normal blood glucose levels,body mass index or the ability to wear normal clothes and eat normal food were the main drivers to taking part in the study. The TDR phase was perceived as challenging but somewhat easier than anticipated. Willpower, use of behaviour–regulation strategies,social roles, behavioural independence and social and clinical support were vital determinants of adherence. Both the TDR and FR stages required resolving cognitive and emotional goal conflicts. Transition to regular food was perceived as destabilising and required increased effort, re-designing of one’s ‘Foodrobe’ and continuous support.
Summary: Experience with the weight loss stage of the DiRECT intervention for diabetes remission was positive for most participants, but clinical and social support proved essential for a successful completion.
Original languageEnglish
Article numberP444
Pages (from-to)176
JournalDiabetic Medicine
Volume35
Issue numberS1
DOIs
Publication statusPublished - 1 Mar 2018
EventDiabetes UK Professional Conference 2018 - London ExCel, London, United Kingdom
Duration: 14 Mar 201816 Mar 2018

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