TY - JOUR
T1 - Reallocating time from sedentary behavior to physical activity in patients with peripheral artery disease
T2 - Analyzing the effects on walking capacity using compositional data analysis
AU - Germano-Soares, Antonio Henrique
AU - Tassitano, Rafael M.
AU - Farah, Breno Quintela
AU - Andrade-Lima, Aluísio
AU - De Almeida Correia, Marília
AU - Gába, Aleš
AU - Štefelová, Nikola
AU - Puech-Leao, Pedro
AU - Wolosker, Nelson
AU - Cucato, Gabriel Grizzo
AU - Ritti-Dias, Raphael Mendes
N1 - Funding Information:
A.H.G.-S. was supported by the Coordination for the Improvement of Higher Education Personnel (CAPES–Master scholarship). G.G.C. holds a grant from The National Council for Scientific and Technological Development (CNPq number 409707/2016-3). R.M.R.-D. holds a research productivity fellowship (PQ-1D) granted by CNPq.
Publisher Copyright:
© 2021 Human Kinetics, Inc.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/4/1
Y1 - 2021/4/1
N2 - Background: To examine the associations between physical activity (PA) and sedentary behavior (SB) with walking capacity and the effects of reallocating time from SB to PA in patients with symptomatic peripheral artery disease (PAD) using compositional data analysis. Methods: This cross-sectional study included 178 patients (34% females, mean age = 66 [9] y, body mass index = 27.8 [5.0] kg/m2, and ankle-brachial index = 0.60 [0.18]). Walking capacity was assessed as the total walking distance (TWD) achieved in a 6-minute walk test, while SB, light-intensity PA, and moderate to vigorous-intensity PA (MVPA) were measured by a triaxial accelerometer and conceptualized as a time-use composition. Associations between time reallocation among wake-time behaviors and TWD were determined using compositional isotemporal substitution models. Results: A positive association of MVPA with TWD (relative to remaining behaviors) was found in men (βilr = 66.9, SE = 21.4, P = .003) and women (βilr = 56.5, SE = 19.8; P = .005). Reallocating 30 minutes per week from SB to MVPA was associated with higher TWD in men (6.7 m; 95% confidence interval, 2.6–10.9 m) and women (4.5 m; 95% confidence interval, 1.5–7.5 m). Conclusions: The findings highlight, using a compositional approach, the beneficial and independent association of MVPA with walking capacity in patients with symptomatic PAD, whereas SB and light-intensity PA were not associated.
AB - Background: To examine the associations between physical activity (PA) and sedentary behavior (SB) with walking capacity and the effects of reallocating time from SB to PA in patients with symptomatic peripheral artery disease (PAD) using compositional data analysis. Methods: This cross-sectional study included 178 patients (34% females, mean age = 66 [9] y, body mass index = 27.8 [5.0] kg/m2, and ankle-brachial index = 0.60 [0.18]). Walking capacity was assessed as the total walking distance (TWD) achieved in a 6-minute walk test, while SB, light-intensity PA, and moderate to vigorous-intensity PA (MVPA) were measured by a triaxial accelerometer and conceptualized as a time-use composition. Associations between time reallocation among wake-time behaviors and TWD were determined using compositional isotemporal substitution models. Results: A positive association of MVPA with TWD (relative to remaining behaviors) was found in men (βilr = 66.9, SE = 21.4, P = .003) and women (βilr = 56.5, SE = 19.8; P = .005). Reallocating 30 minutes per week from SB to MVPA was associated with higher TWD in men (6.7 m; 95% confidence interval, 2.6–10.9 m) and women (4.5 m; 95% confidence interval, 1.5–7.5 m). Conclusions: The findings highlight, using a compositional approach, the beneficial and independent association of MVPA with walking capacity in patients with symptomatic PAD, whereas SB and light-intensity PA were not associated.
KW - Accelerometry
KW - Movement behaviors
KW - Time use
KW - Walking impairment
UR - http://www.scopus.com/inward/record.url?scp=85104047188&partnerID=8YFLogxK
U2 - 10.1123/JPAH.2020-0487
DO - 10.1123/JPAH.2020-0487
M3 - Article
C2 - 33668017
AN - SCOPUS:85104047188
SN - 1543-3080
VL - 18
SP - 426
EP - 432
JO - Journal of Physical Activity and Health
JF - Journal of Physical Activity and Health
IS - 4
ER -