Reduced self-perception of fatigue after intake of panax ginseng root extract (G115®) formulated with vitamins and minerals—an open-label study

Anne Laure Tardy*, Beatrice Bois De Fer, Salvador Cañigueral, David Kennedy, Andrew Scholey, Simon Hitier, Alexia Aran, Etienne Pouteau

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Unexplained fatigue is a common complaint. When underlying disease causes have been eliminated, lifestyle measures and supplementation can be indicated. Elaborating on clinical findings that G115®, a dry extract from the root of Panax ginseng, combined with vitamins and minerals could alleviate fatigue, this open label study aimed at assessing its effect on perceived fatigue and energy. Methods: Healthy adults self-reporting fatigue (n = 103) completed the Multidimensional Fatigue Inventory questionnaire. They rated their perceptions of mental and physical fatigue, energy, performance, and stress at baseline and 15, 30, 60 and 90 days after a daily intake of 40 mg G115® formulated with vitamins and minerals. Results: Compared with baseline values, mean self-perception of general fatigue was reduced by −7.55 units [95% CI: −8.44; −6.66] (−41.8%, p < 0.0001) at 90 days. All assessed perception ratings (mental and physical fatigue, reduced activity and motivation, performance, and stress) were significantly and steadily improved from two weeks after supplementation up to study’s end. Overall satisfaction with the ability of the product to reduce fatigue reached 85% at Day 90. Conclusion: Daily intake with G115® extract formulated with vitamins and minerals suggests an improvement of self-perception of fatigue and energy in a fatigued adult population.

Original languageEnglish
Article number6257
Pages (from-to)1-10
Number of pages10
JournalInternational Journal of Environmental Research and Public Health
Volume18
Issue number12
DOIs
Publication statusPublished - 9 Jun 2021

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