Reversing microcrystalline tests-An analytical approach to recycling of microcrystals from drugs of abuse

Leonie E. Elie; Mark G. Baron; Ruth S. Croxton; Mathieu P. Elie

doi:10.1016/j.forsciint.2011.01.008

Reversing microcrystalline tests-An analytical approach to recycling of microcrystals from drugs of abuse

Leonie E. Elie^*, Mark G. Baron, Ruth S. Croxton, Mathieu P. Elie

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

A combined analysis of microcrystalline tests followed by LC-MS or GC-MS analysis is described. Microcrystalline tests are shown to be non-destructive as addition products formed were easily dissociated after the application of an appropriate solvent. Subsequent analysis of the sample was done to quantify the recovery of the drug. Examples were performed using the date rape drug γ-hydroxybutyrate (GHB) and the synthetic opioid methadone.

Original language	English
Pages (from-to)	e55-e58
Journal	Forensic Science International
Volume	207
Issue number	1-3
Early online date	1 Feb 2011
DOIs	https://doi.org/10.1016/j.forsciint.2011.01.008
Publication status	Published - 15 Apr 2011
Externally published	Yes

Keywords

Drugs of abuse
GC-MS
GHB
LC-MS
Methadone
Microcrystalline test

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.forsciint.2011.01.008

https://eprints.lincoln.ac.uk/id/eprint/3957/

Cite this

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title = "Reversing microcrystalline tests-An analytical approach to recycling of microcrystals from drugs of abuse",

abstract = "A combined analysis of microcrystalline tests followed by LC-MS or GC-MS analysis is described. Microcrystalline tests are shown to be non-destructive as addition products formed were easily dissociated after the application of an appropriate solvent. Subsequent analysis of the sample was done to quantify the recovery of the drug. Examples were performed using the date rape drug γ-hydroxybutyrate (GHB) and the synthetic opioid methadone.",

keywords = "Drugs of abuse, GC-MS, GHB, LC-MS, Methadone, Microcrystalline test",

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AU - Elie, Leonie E.

AU - Baron, Mark G.

AU - Croxton, Ruth S.

AU - Elie, Mathieu P.

PY - 2011/4/15

Y1 - 2011/4/15

N2 - A combined analysis of microcrystalline tests followed by LC-MS or GC-MS analysis is described. Microcrystalline tests are shown to be non-destructive as addition products formed were easily dissociated after the application of an appropriate solvent. Subsequent analysis of the sample was done to quantify the recovery of the drug. Examples were performed using the date rape drug γ-hydroxybutyrate (GHB) and the synthetic opioid methadone.

AB - A combined analysis of microcrystalline tests followed by LC-MS or GC-MS analysis is described. Microcrystalline tests are shown to be non-destructive as addition products formed were easily dissociated after the application of an appropriate solvent. Subsequent analysis of the sample was done to quantify the recovery of the drug. Examples were performed using the date rape drug γ-hydroxybutyrate (GHB) and the synthetic opioid methadone.

KW - Drugs of abuse

KW - GC-MS

KW - GHB

KW - LC-MS

KW - Methadone

KW - Microcrystalline test

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U2 - 10.1016/j.forsciint.2011.01.008

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M3 - Article

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SN - 0379-0738

VL - 207

SP - e55-e58

JO - Forensic Science International

JF - Forensic Science International

IS - 1-3

ER -

Reversing microcrystalline tests-An analytical approach to recycling of microcrystals from drugs of abuse

Abstract

Keywords

UN SDGs

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