TY - JOUR
T1 - Risk Factors for Mobility Decline in Community-Dwelling Older Adults
T2 - A Systematic Literature Review
AU - Nicolson, Philippa J.A.
AU - Sanchez-Santos, Maria T.
AU - Bruce, Julie
AU - Kirtley, Shona
AU - Ward, Lesley
AU - Williamson, Esther
AU - Lamb, Sarah E.
N1 - Funding information: The authors do not have any conflicts of interest to declare. SL and EW receive funding from the Collaboration for Leadership in Applied Health Research and Care Oxford at Oxford Health NHS Foundation Trust, and SL, MS, and EW are supported by NIHR Musculoskeletal Biomedical Research Centre, Oxford. PN is funded by a Versus Arthritis Foundation Fellowship (Grant Reference Number 22428). JB is supported by NIHR Research Capability Funding via University Hospitals Coventry and Warwickshire. SK is funded by Cancer Research UK (Grant C49297/A27294). The funders had no role in the design, collection, analysis, or reporting of this review. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care.
PY - 2021/12/1
Y1 - 2021/12/1
N2 - Mobility is essential to maintaining independence for older adults. This systematic review aimed to summarize evidence about self-reported risk factors for self-reported mobility decline; and to provide an overview of published prognostic models for self-reported mobility decline among community-dwelling older adults. Databases were searched from inception to June 2, 2020. Studies were screened by two independent reviewers who extracted data and assessed study quality. Sixty-one studies (45,187 participants) were included, providing information on 107 risk factors. High-quality evidence and moderate/large effect sizes for the association with mobility decline were found for older age beyond 75 years, the presence of widespread pain, and mobility modifications. Moderate-high quality evidence and small effect sizes were found for a further 21 factors. Three model development studies demonstrated acceptable model performance, limited by high risk of bias. These findings should be considered in intervention development, and in developing a prediction instrument for practical application.
AB - Mobility is essential to maintaining independence for older adults. This systematic review aimed to summarize evidence about self-reported risk factors for self-reported mobility decline; and to provide an overview of published prognostic models for self-reported mobility decline among community-dwelling older adults. Databases were searched from inception to June 2, 2020. Studies were screened by two independent reviewers who extracted data and assessed study quality. Sixty-one studies (45,187 participants) were included, providing information on 107 risk factors. High-quality evidence and moderate/large effect sizes for the association with mobility decline were found for older age beyond 75 years, the presence of widespread pain, and mobility modifications. Moderate-high quality evidence and small effect sizes were found for a further 21 factors. Three model development studies demonstrated acceptable model performance, limited by high risk of bias. These findings should be considered in intervention development, and in developing a prediction instrument for practical application.
KW - mobility disability
KW - predictors
KW - self-reported
UR - http://www.scopus.com/inward/record.url?scp=85122487999&partnerID=8YFLogxK
U2 - 10.1123/japa.2020-0482
DO - 10.1123/japa.2020-0482
M3 - Article
C2 - 34348224
AN - SCOPUS:85122487999
SN - 1063-8652
VL - 29
SP - 1053
EP - 1066
JO - Journal of Aging and Physical Activity
JF - Journal of Aging and Physical Activity
IS - 6
ER -