This paper reports an experimental and numerical investigation on the scaling effects in the flow hydrodynamics for confined microdroplets induced by a surface acoustic wave (SAW). The characteristic parameters of the flow hydrodynamics were studied as a function of the separation height, H, between the LiNbO3 substrate and a top glass plate, for various droplets volumes and radio-frequency powers. The ratio of the gap height to attenuation length of the SAW, H/l SAW, is shown to be an important parameter affecting the streaming flow induced in this confined regime. The reported numerical and experimental results are in good agreement over the range examined in this study and demonstrate that, at a lower gap heights of H ≤ 100 μm, a significant decrease in streaming velocity or Reynolds number is induced, with the velocity approaching zero when the gap height is decreased to ~50 μm. An increase in the gap height results in an increased streaming velocity; however, if the gap height exceeds 70 % of the SAW attenuation length, any further increase in the gap height induces a drop in the streaming velocity.