Shigella sonnei genome sequencing and phylogenetic analysis indicate recent global dissemination from Europe

Kathryn Holt, Stephen Baker, François-Xavier Weill, Edward Holmes, Andrew Kitchen, Jun Yu, Vartul Sangal, Derek Brown, John Coia, Dong-Wook Kim, Seon Young Choi, Su Hee Kim, Wanderley da Silveira, Derek Pickard, Jeremy Farrar, Julian Parkhill, Gordon Dougan, Nicholas Thomson

Research output: Contribution to journalArticlepeer-review

176 Citations (Scopus)

Abstract

Nicholas Thomson and colleagues report whole-genome sequencing of 132 globally distributed isolates of Shigella sonnei, a cause of human dysentery. Their phylogeographic analyses suggest that the current S. sonnei population is under 500 years old, and the authors are able to trace several distinct lineages that have spread out of Europe to other continents over the last few decades.
Original languageEnglish
Pages (from-to)1056-1059
JournalNature Genetics
Volume44
Issue number9
DOIs
Publication statusPublished - Sep 2012

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