Optical fiber based twist sensors usually suffer from high cross sensitivity to strain. Here we report a strain independent twist sensor based on an uneven platinum coated hollow core fiber (HCF) structure. The sensor is fabricated by splicing a section of ~4.5-mm long HCF between two standard single mode fibers, followed by a sputter-coating of a very thin layer of platinum on both sides of the HCF surface. Experimental results demonstrate that twist angles can be measured by monitoring the strength change of transmission spectral dip. The sensor’s cross sensitivity to strain is investigated before and after coating with platinum. It is found that by coating a platinum layer of ~9 nm on the HCF surface, sensor’s cross sensitivity to strain is significantly decreased with over two orders of magnitude less than that of the uncoated sensor sample. The lowest strain sensitivity of ~ 2.32 × 10-5 dB/με has been experimentally achieved, which is to the best of our knowledge, the lowest cross sensitivity to strain reported to date for optical fiber sensors based on intensity modulation. In addition, the proposed sensor is capable of simultaneous measurement of strain and twist angle by monitoring the wavelength shift and dip strength variation of a single spectral dip. In the experiment, strain and twist angle sensitivities of 0.61 pm/με and 0.10 dB/° have been achieved. Moreover, the proposed sensor offers advantages of ease of fabrication, miniature size and a good repeatability of measurement.