Superhydrophobic surfaces for microfluidic applications

Yasemin Koç; Paul Roach; Carole Perry; Michael Newton; Glen McHale; Andrew de Mello; Neil Shirtcliffe

Superhydrophobic surfaces for microfluidic applications

Yasemin Koç, Paul Roach, Carole Perry, Michael Newton, Glen McHale, Andrew de Mello, Neil Shirtcliffe

Mathematics, Physics and Electrical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Protein adsorption is of major importance in many contemporary research fields including biotechnology and materials science. Chemical modification of surfaces provides a simple and direct way of controlling the nature of protein surface interactions. In the current studies, we demonstrate the use of superhydrophobic surfaces within microfluidic systems to allow almost complete removal of adsorbed protein under flow conditions. Our aim is to use such 'surface technology' in PCR microfluidic devices for continuous flow PCR to hinder enzyme loss due to adsorption and therefore increase the efficiency of the reaction.

Original language	English
Title of host publication	Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference: 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Japan Academic Association
Pages	200-202
Number of pages	3
Publication status	Published - 2006
Event	10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Tokyo, Japan Duration: 5 Nov 2006 → 9 Nov 2006

Conference

Conference	10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
Country/Territory	Japan
City	Tokyo
Period	5/11/06 → 9/11/06

Keywords

PCR
Superhydrophobic surfaces
Surface adsorption
ZnO

Cite this

@inproceedings{49e6d2b689934bb7b670ad8f883540ff,

title = "Superhydrophobic surfaces for microfluidic applications",

abstract = "Protein adsorption is of major importance in many contemporary research fields including biotechnology and materials science. Chemical modification of surfaces provides a simple and direct way of controlling the nature of protein surface interactions. In the current studies, we demonstrate the use of superhydrophobic surfaces within microfluidic systems to allow almost complete removal of adsorbed protein under flow conditions. Our aim is to use such 'surface technology' in PCR microfluidic devices for continuous flow PCR to hinder enzyme loss due to adsorption and therefore increase the efficiency of the reaction.",

keywords = "PCR, Superhydrophobic surfaces, Surface adsorption, ZnO",

author = "Yasemin Ko{\c c} and Paul Roach and Carole Perry and Michael Newton and Glen McHale and {de Mello}, Andrew and Neil Shirtcliffe",

year = "2006",

language = "English",

pages = "200--202",

booktitle = "Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference: 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

publisher = "Japan Academic Association",

note = "10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 ; Conference date: 05-11-2006 Through 09-11-2006",

}

Koç, Y, Roach, P, Perry, C, Newton, M, McHale, G, de Mello, A & Shirtcliffe, N 2006, Superhydrophobic surfaces for microfluidic applications. in Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference: 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Japan Academic Association, pp. 200-202, 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006, Tokyo, Japan, 5/11/06.

Superhydrophobic surfaces for microfluidic applications. / Koç, Yasemin; Roach, Paul; Perry, Carole et al.
Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference: 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Japan Academic Association, 2006. p. 200-202.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Superhydrophobic surfaces for microfluidic applications

AU - Koç, Yasemin

AU - Roach, Paul

AU - Perry, Carole

AU - Newton, Michael

AU - McHale, Glen

AU - de Mello, Andrew

AU - Shirtcliffe, Neil

PY - 2006

Y1 - 2006

N2 - Protein adsorption is of major importance in many contemporary research fields including biotechnology and materials science. Chemical modification of surfaces provides a simple and direct way of controlling the nature of protein surface interactions. In the current studies, we demonstrate the use of superhydrophobic surfaces within microfluidic systems to allow almost complete removal of adsorbed protein under flow conditions. Our aim is to use such 'surface technology' in PCR microfluidic devices for continuous flow PCR to hinder enzyme loss due to adsorption and therefore increase the efficiency of the reaction.

AB - Protein adsorption is of major importance in many contemporary research fields including biotechnology and materials science. Chemical modification of surfaces provides a simple and direct way of controlling the nature of protein surface interactions. In the current studies, we demonstrate the use of superhydrophobic surfaces within microfluidic systems to allow almost complete removal of adsorbed protein under flow conditions. Our aim is to use such 'surface technology' in PCR microfluidic devices for continuous flow PCR to hinder enzyme loss due to adsorption and therefore increase the efficiency of the reaction.

KW - PCR

KW - Superhydrophobic surfaces

KW - Surface adsorption

KW - ZnO

UR - http://www.scopus.com/inward/record.url?scp=84902440419&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:84902440419

SP - 200

EP - 202

BT - Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference: 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences

PB - Japan Academic Association

T2 - 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006

Y2 - 5 November 2006 through 9 November 2006

ER -

Superhydrophobic surfaces for microfluidic applications

Abstract

Conference

Keywords

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