Surface treatment using laser assisted processes such as laser cladding are amongst the fastest growing research areas. Laser cladding has become a more sustainable material processing route with the development of more powerful and improved gas and solid state lasers. This technology is a single step process that is capable of improving the reliability of metal components in a variety of applications and also used for component repair. In this study, 17-4 precipitation hardening stainless steel powder was deposited on commercially pure Titanium alloy substrate by laser cladding. The influence of process variable on clad integrity and mechanical property was investigated. The laser power was varied between 1000–1400 W, while other associated process variables were fixed at constant values. The study revealed that increasing the laser power resulted in improved clad quality and no significant relationship was observed between laser power and microhardness of the specimens.