Synthesis of functionalised bipyridines by sequential nucleophilic substitution of hydrogen and cycloaddition in 1,2,4-triazine rings

Dmitry N. Kozhevnikov, Valery N. Kozhevnikov, Tatiana V. Nikitina, Vladimir L. Rusinov*, Oleg N. Chupakhin, Hans Neunhoeffer*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

A new methodology for the synthesis of functionalised bipyridines by the direct cyanation of 3-(2-pyridyl)-1,2,4-triazine 4-oxide through nucleophilic substitution for hydrogen followed by the transformation of the 1,2,4-triazine ring into the pyridine ring by the Diels-Alder reaction and, finally, the chemical conversion of the cyano group is described.

Original languageEnglish
Pages (from-to)30-31
Number of pages2
JournalMendeleev Communications
Volume12
Issue number1
DOIs
Publication statusPublished - 2002
Externally publishedYes

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