Abstract
Most immune responses associated with vaccination are controlled by specific T cells of a CD4 + helper phenotype which mediate the generation of effector antibodies, cytotoxic T lymphocytes (CTLs), or the activation of innate immune effector cells. A rapidly growing understanding of the generation, maintenance, activity, and measurement of such T cells is leading to vaccination strategies with greater efficacy and potentially greater microbial coverage.
Original language | English |
---|---|
Article number | 84 |
Journal | Vaccines |
Volume | 6 |
Issue number | 4 |
DOIs | |
Publication status | Published - 14 Dec 2018 |
Keywords
- Effectors
- Memory
- T cells
- Vaccines