The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Yifan Li, Ekaterina McKenna, William Parkes, Andrew Pitt, Anthony Walton

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

A protein microarray hybridisation system has been implemented by employing patterned hydrophobic thin films on hydrophilic substrates as a means of confinement for aqueous samples. This approach has the ability to handle, and keep separate, small sample volumes of just a few microlitres. In addition, the system is more straight forward to use than the existing multi-well gasket solution. The paper describes the fabrication method and the system is demonstrated for a model protein microarray assay.
Original languageEnglish
Pages (from-to)073703
JournalApplied Physics Letters
Volume99
Issue number7
DOIs
Publication statusPublished - 2011

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