The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Yifan Li; Ekaterina McKenna; William Parkes; Andrew Pitt; Anthony Walton

doi:10.1063/1.3626037

The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Yifan Li, Ekaterina McKenna, William Parkes, Andrew Pitt, Anthony Walton

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

A protein microarray hybridisation system has been implemented by employing patterned hydrophobic thin films on hydrophilic substrates as a means of confinement for aqueous samples. This approach has the ability to handle, and keep separate, small sample volumes of just a few microlitres. In addition, the system is more straight forward to use than the existing multi-well gasket solution. The paper describes the fabrication method and the system is demonstrated for a model protein microarray assay.

Original language	English
Pages (from-to)	073703
Journal	Applied Physics Letters
Volume	99
Issue number	7
DOIs	https://doi.org/10.1063/1.3626037
Publication status	Published - 2011

Access to Document

10.1063/1.3626037

Cite this

@article{07c054b0f5134fbdb592a39698ce0c19,

title = "The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays",

abstract = "A protein microarray hybridisation system has been implemented by employing patterned hydrophobic thin films on hydrophilic substrates as a means of confinement for aqueous samples. This approach has the ability to handle, and keep separate, small sample volumes of just a few microlitres. In addition, the system is more straight forward to use than the existing multi-well gasket solution. The paper describes the fabrication method and the system is demonstrated for a model protein microarray assay.",

author = "Yifan Li and Ekaterina McKenna and William Parkes and Andrew Pitt and Anthony Walton",

year = "2011",

doi = "10.1063/1.3626037",

language = "English",

volume = "99",

pages = "073703",

journal = "Applied Physics Letters",

issn = "0003-6951",

publisher = "American Institute of Physics",

number = "7",

}

TY - JOUR

T1 - The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

AU - Li, Yifan

AU - McKenna, Ekaterina

AU - Parkes, William

AU - Pitt, Andrew

AU - Walton, Anthony

PY - 2011

Y1 - 2011

N2 - A protein microarray hybridisation system has been implemented by employing patterned hydrophobic thin films on hydrophilic substrates as a means of confinement for aqueous samples. This approach has the ability to handle, and keep separate, small sample volumes of just a few microlitres. In addition, the system is more straight forward to use than the existing multi-well gasket solution. The paper describes the fabrication method and the system is demonstrated for a model protein microarray assay.

AB - A protein microarray hybridisation system has been implemented by employing patterned hydrophobic thin films on hydrophilic substrates as a means of confinement for aqueous samples. This approach has the ability to handle, and keep separate, small sample volumes of just a few microlitres. In addition, the system is more straight forward to use than the existing multi-well gasket solution. The paper describes the fabrication method and the system is demonstrated for a model protein microarray assay.

UR - https://www.scopus.com/pages/publications/80052085514

U2 - 10.1063/1.3626037

DO - 10.1063/1.3626037

M3 - Article

SN - 0003-6951

VL - 99

SP - 073703

JO - Applied Physics Letters

JF - Applied Physics Letters

IS - 7

ER -

The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Abstract

Access to Document

Other files and links

Fingerprint

Cite this