Fruits and vegetables rich in flavonoids have been related to the reduction in the incidence of CVD in several epidemiological studies. Flavonoids are a group of phenolic compounds with strong antioxidant activity. Thus, the protective effects of the flavonoids could be a result of their ability to scavenge reactive oxygen and nitrogen species, which are formed during intracellular oxidative stress. However, postprandial effects on antioxidant status after consumption of fruits and juices are controversial. In addition, very little is known about the amount of flavonoids absorbed from the diet and the reliability of plasma biomarkers. Consequently, the aim of the present study was to investigate the beneficial effects of an acute intervention with flavonoid-rich juices on markers of oxidative stress and cardiovascular risk factors.