The effect of ex vivo lung perfusion on proinflammatory and anti-inflammatory cytokines in the human lung

Danai Karamanou; S. Bean; Mahesh Prabhu; Hannah Walden; Stephen Clark; Paul Corris; John Dark; Andrew Fisher

doi:10.1136/thx.2009.127068p

The effect of ex vivo lung perfusion on proinflammatory and anti-inflammatory cytokines in the human lung

Danai Karamanou, S. Bean, Mahesh Prabhu, Hannah Walden, Stephen Clark, Paul Corris, John Dark, Andrew Fisher

Research output: Contribution to journal › Article › peer-review

Abstract

Ex vivo lung perfusion (EVLP) is an emerging technique for the re-conditioning of damaged donor lungs prior to transplantation. Previous work has demonstrated improvement in gas exchange in lungs subjected to this technique; however, the effect of EVLP on inflammation has not yet been examined. We hypothesised that a potential benefit of EVLP in re-conditioning donor lungs may be due to modification of the inflammatory profile.

Original language	English
Pages (from-to)	A25
Journal	Thorax
Volume	64
Issue number	S4
DOIs	https://doi.org/10.1136/thx.2009.127068p
Publication status	Published - 2009

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10.1136/thx.2009.127068p

http://thorax.bmj.com/content/64/Suppl_4/A23.full

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title = "The effect of ex vivo lung perfusion on proinflammatory and anti-inflammatory cytokines in the human lung",

abstract = "Ex vivo lung perfusion (EVLP) is an emerging technique for the re-conditioning of damaged donor lungs prior to transplantation. Previous work has demonstrated improvement in gas exchange in lungs subjected to this technique; however, the effect of EVLP on inflammation has not yet been examined. We hypothesised that a potential benefit of EVLP in re-conditioning donor lungs may be due to modification of the inflammatory profile.",

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AU - Karamanou, Danai

AU - Bean, S.

AU - Prabhu, Mahesh

AU - Walden, Hannah

AU - Clark, Stephen

AU - Corris, Paul

AU - Dark, John

AU - Fisher, Andrew

PY - 2009

Y1 - 2009

N2 - Ex vivo lung perfusion (EVLP) is an emerging technique for the re-conditioning of damaged donor lungs prior to transplantation. Previous work has demonstrated improvement in gas exchange in lungs subjected to this technique; however, the effect of EVLP on inflammation has not yet been examined. We hypothesised that a potential benefit of EVLP in re-conditioning donor lungs may be due to modification of the inflammatory profile.

AB - Ex vivo lung perfusion (EVLP) is an emerging technique for the re-conditioning of damaged donor lungs prior to transplantation. Previous work has demonstrated improvement in gas exchange in lungs subjected to this technique; however, the effect of EVLP on inflammation has not yet been examined. We hypothesised that a potential benefit of EVLP in re-conditioning donor lungs may be due to modification of the inflammatory profile.

U2 - 10.1136/thx.2009.127068p

DO - 10.1136/thx.2009.127068p

M3 - Article

SN - 0040-6376

VL - 64

SP - A25

JO - Thorax

JF - Thorax

IS - S4

ER -

The effect of ex vivo lung perfusion on proinflammatory and anti-inflammatory cytokines in the human lung

Abstract

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