The effect of ex vivo lung perfusion on proinflammatory and anti-inflammatory cytokines in the human lung

Danai Karamanou, S. Bean, Mahesh Prabhu, Hannah Walden, Stephen Clark, Paul Corris, John Dark, Andrew Fisher

Research output: Contribution to journalArticlepeer-review

Abstract

Ex vivo lung perfusion (EVLP) is an emerging technique for the re-conditioning of damaged donor lungs prior to transplantation. Previous work has demonstrated improvement in gas exchange in lungs subjected to this technique; however, the effect of EVLP on inflammation has not yet been examined. We hypothesised that a potential benefit of EVLP in re-conditioning donor lungs may be due to modification of the inflammatory profile.
Original languageEnglish
Pages (from-to)A25
JournalThorax
Volume64
Issue numberS4
DOIs
Publication statusPublished - 2009

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