The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behavior

Ann Katrin Kraeuter, Paul C. Guest, Zoltán Sarnyai

Research output: Chapter in Book/Report/Conference proceedingChapter

54 Citations (Scopus)

Abstract

The open field test is used in studies of the neurobiological basis of anxiety and screening for novel drug targets and anxiolytic compounds. This test uses a camera to measure movement of the test animal in the peripheral and central zones of a 42 × 42 × 42 cm polyvinyl chloride box. This chapter describes a protocol for carrying out the open-field test for assessment of locomotion and anxiety-like behavior in mice.
Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages99-103
Number of pages5
DOIs
Publication statusPublished - 2019

Publication series

NameMethods in Molecular Biology
Volume1916

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