The recent advances in the mathematical modelling of human pluripotent stem cells

Laura E. Wadkin, Sirio Orozco-Fuentes, Irina Neganova, Majlinda Lako, Anvar Shukurov, Nicholas G. Parker

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
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Abstract

Human pluripotent stem cells hold great promise for developments in regenerative medicine and drug design. The mathematical modelling of stem cells and their properties is necessary to understand and quantify key behaviours and develop non-invasive prognostic modelling tools to assist in the optimisation of laboratory experiments. Here, the recent advances in the mathematical modelling of hPSCs are discussed, including cell kinematics, cell proliferation and colony formation, and pluripotency and differentiation.
Original languageEnglish
Article number276
Number of pages14
JournalSN Applied Sciences
Volume2
Issue number2
Early online date27 Jan 2020
DOIs
Publication statusPublished - Feb 2020
Externally publishedYes

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