The Therapeutic Potential of Ketogenic Diet Throughout Life: Focus on Metabolic, Neurodevelopmental and Neurodegenerative Disorders

Ann Katrin Kraeuter, Paul C. Guest, Zoltan Sarnyai

Research output: Chapter in Book/Report/Conference proceedingChapter

15 Citations (Scopus)

Abstract

This chapter reviews the efficacy of the ketogenic diet in a variety of neurodegenerative, neurodevelopmental and metabolic conditions throughout different stages of life. It describes conditions affecting children, metabolic disorders in adults and disorderrs affecting the elderly. We have focused on application of the ketogenic diet in clinical studies and in preclinical models and discuss the benefits and negative aspects of the diet. Finally, we highlight the need for further research in this area with a view of discovering novel mechanistic targets of the ketogenic diet, as a means of maximising the potential benefits/risks ratio.
Original languageEnglish
Title of host publicationReviews on Biomarker Studies in Aging and Anti-Aging Research
EditorsPaul C. Guest
Place of PublicationCham
PublisherSpringer
Chapter5
Pages77-101
Number of pages25
ISBN (Electronic)9783030256500
ISBN (Print)9783030256494
DOIs
Publication statusPublished - 7 Sept 2019
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1178

Keywords

  • Biomarker
  • Disease
  • Drug development
  • Drug target
  • Ketogenic diet
  • Life stages

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