The aim of this paper is to present an approach for comprehending affordable housing. The approach is based on a new paradigm of research: trans-disciplinarity; a form of inquiry that crosses the boundaries of different disciplines. An argument on the impact of trans-disciplinary thinking on understanding affordable housing is developed, then is placed within the perspective of how lifestyle theories and their underlying concepts can be integrated into a comprehensive investigatory process. In turn, a framework of inquiry is developed while reflected on affordable housing knowledge types. An interpretation of the framework into a survey tool is conceptualized. The tool is introduced in the form of a questionnaire to be implemented in different contexts. The testing of the questionnaire as a tool of inquiry reveals its validity, corroborates the value of integrating trans-disciplinary knowledge into affordable housing research, and accentuates the value of introducing lifestyle theories as a new form of knowledge necessary for future inquiry on affordable housing.