Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

Rudolf S.N. Fehrmann, Ritsert C. Jansen, Jan H. Veldink, Harm-Jan Westra, Danny Arends, Marc Jan Bonder, Jingyuan Fu, Patrick Deelen, Harry J.M. Groen, Asia Smolonska, Rinse K. Weersma, Robert M.W. Hofstra, Wim A. Buurman, Sander Rensen, Marcel G.M. Wolfs, Mathieu Platteel, Alexandra Zhernakova, Clara C. Elbers, Eleanora M. Festen, Gosia TrynkaMarten H. Hofker, Christiaan G.J. Saris, Roel A. Ophoff, Leonard H. van den Berg, David A. van Heel, Cisca Wijmenga, Gerard J. te Meerman, Lude Franke*

*Corresponding author for this work

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274 Citations (Scopus)
  • 274 Citations
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  • 2015

    Cell Specific eQTL Analysis without Sorting Cells

    Westra, H. J., Arends, D., Esko, T., Peters, M. J., Schurmann, C., Schramm, K., Kettunen, J., Yaghootkar, H., Fairfax, B. P., Andiappan, A. K., Li, Y., Fu, J., Karjalainen, J., Platteel, M., Visschedijk, M., Weersma, R. K., Kasela, S., Milani, L., Tserel, L. & Peterson, P. & 38 others, Reinmaa, E., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Homuth, G., Petersmann, A., Lorbeer, R., Prokisch, H., Meitinger, T., Herder, C., Roden, M., Grallert, H., Ripatti, S., Perola, M., Wood, A. R., Melzer, D., Ferrucci, L., Singleton, A. B., Hernandez, D. G., Knight, J. C., Melchiotti, R., Lee, B., Poidinger, M., Zolezzi, F., Larbi, A., Wang, D. Y., van den Berg, L. H., Veldink, J. H., Rotzschke, O., Makino, S., Salomaa, V., Strauch, K., Völker, U., van Meurs, J. B. J., Metspalu, A., Wijmenga, C., Jansen, R. C. & Franke, L., 8 May 2015, In: PLoS Genetics. 11, 5, 17 p., e1005223.

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    Open Access
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    81 Citations (Scopus)
    15 Downloads (Pure)
  • 2014

    High-throughput computational methods and software for quantitative trait locus (QTL) mapping

    Arends, D., 2014, 1 ed. Groningen: Danny Arends. 169 p.

    Research output: Book/Report › Book › peer-review

    Open Access