Transcranial direct current stimulation suggests not improving postural control during adapted tandem position in people with Parkinson's disease: A pilot study

Beatriz Regina Legutke, Lilian Teresa Bucken Gobbi, Diego Orcioli-Silva, Paulo Cezar Rocha dos Santos, Gabriel Antonio Gazziero Moraca, Rodrigo Vitório, Victor Spiandor Beretta*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Background Balance impairments in people with Parkinson's disease (PD) demonstrated mainly in challenging postural tasks, such as increased body oscillation may be attributed to the deficits in the brain structures functionality involved in postural control (e.g., motor cortex, midbrain, and brainstem). Although promising results, the effect of transcranial direct current stimulation (tDCS) on postural control in people with PD is unclear, especially in objective measures such as the center of pressure (CoP) parameters. Thus, we analyzed the effects of a single session of tDCS on the CoP parameters during the adapted tandem position in people with PD. Methods Nineteen people with PD participated in this crossover, randomized, and double-blind study. Anodal tDCS was applied over the primary motor cortex in two conditions of stimulation (2 mA/active and sham) on two different days for 20 min immediately before the postural control evaluation. Participants remained standing in an adapted tandem position for the postural control assessment for 30 s (three trials). CoP parameters were acquired by a force plate. Results No significant differences were demonstrated between stimulation conditions (p-value range = 0.15–0.89). Conclusions Our results suggested that a single session of tDCS with 2 mA does not improve the postural control of people with PD during adapted tandem.
Original languageEnglish
Article number114581
JournalBehavioural Brain Research
Volume452
Early online date13 Jul 2023
DOIs
Publication statusPublished - 24 Aug 2023

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