Translational Medicine. A target for pharmacological intervention in an untreatable human disease

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)
Original languageEnglish
Pages (from-to)1192
JournalScience
Volume346
Issue number6214
DOIs
Publication statusPublished - 5 Dec 2014
Externally publishedYes

Keywords

  • Animals
  • Caloric Restriction
  • Disease Models, Animal
  • Dose-Response Relationship, Drug
  • Electron Transport Complex I/genetics
  • Humans
  • Leigh Disease/drug therapy
  • Mice
  • Molecular Targeted Therapy
  • Saccharomyces cerevisiae/genetics
  • Sirolimus/administration & dosage
  • TOR Serine-Threonine Kinases/antagonists & inhibitors

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