Unexpected Formation of 10-Iodo- and 10-Chlorocamphor under Halosulfonylation Conditions, and Convenient Routes to 10-Chloro- and 10-Bromocamphor

Frank Lewis, Gilles Egron, David Grayson

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)
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Abstract

The generation of camphor-10-sulfonyl iodide in situ under halosulfonylation conditions or exposure of camphor-10-sulfonyl chloride to copper(II) chloride under Asscher–Vofsi conditions leads unexpectedly to the formation of 10-iodocamphor or 10-chlorocamphor, respectively. Additionally, convenient syntheses of 10-bromocamphor and 10-chlorocamphor have been achieved by extension of a previously reported methodology.
Original languageEnglish
Pages (from-to)1531-1535
JournalTetrahedron: Asymmetry
Volume20
Issue number13
DOIs
Publication statusPublished - 2009

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