Using Batch Reactor Results to Calculate Optimal Flow Rates for the Scale-Up of UV Photochemical Reactions

Jonathan Knowles, Luke Elliott, Callum Stacey, Kevin Booker-Milburn

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)
6 Downloads (Pure)

Abstract

The perceived difficulty of the scale-up of photochemistry is one of the main obstacles preventing its widespread use. Herein, we take three different challenging reactions and show that they can be reliably scaled, from immersion well batch reactors to higher power FEP flow reactors. Key to the success has been the development of a powerful calculation methodology which enables the accurate calculation of reactor flow rates from these and previously optimised batch reactions. Despite the challenging nature of these systems, in all cases tens of grams of material was obtained.
Original languageEnglish
Pages (from-to)86-93
JournalReaction Chemistry and Engineering
Volume3
Issue number1
Early online date3 Jan 2018
DOIs
Publication statusPublished - 1 Feb 2018

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