Vitamin D: Implications for ocular disease and therapeutic potential

Rose Reins, Alison McDermott

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)

Abstract

Vitamin D is a multifunctional hormone that is now known to play a significant role in a variety of biological functions in addition to its traditional role in regulating calcium homeostasis. There are a large number of studies demonstrating that adequate vitamin D levels are important in maintaining health and show that vitamin D is able to be utilized at local tissue sites. In the eye, we have increasing evidence of the association between disease and vitamin D. In this narrative review, we summarize recent findings on vitamin D and its relationship to various ocular pathologies and the therapeutic potential for some of these, as well as examine the basic science studies that demonstrate that vitamin D is biologically relevant in the eye.
Original languageEnglish
Pages (from-to)101-110
JournalExperimental Eye Research
Volume134
Early online date25 Feb 2015
DOIs
Publication statusPublished - 1 May 2015

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