TY - JOUR
T1 - Walking training at the heart rate of pain threshold improves cardiovascular function and autonomic regulation in intermittent claudication
T2 - A randomized controlled trial
AU - Chehuen, Marcel
AU - Cucato, Gabriel G
AU - Carvalho, Celso Ricardo F
AU - Ritti-Dias, Raphael M
AU - Wolosker, Nelson
AU - Leicht, Anthony S
AU - Forjaz, Cláudia Lúcia M
N1 - Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.
PY - 2017/10/1
Y1 - 2017/10/1
N2 - OBJECTIVES: This study investigated the effects of walking training (WT) on cardiovascular function and autonomic regulation in patents with intermittent claudication (IC).DESIGN: Randomized controlled trial.METHODS: Forty-two male patients with IC (≥50years) were randomly allocated into two groups: control (CG, n=20, 30min of stretching exercises) and WT (WTG, n=22, 15 bouts of 2min of walking interpolated by 2min of upright rest-walking intensity was set at the heart rate of pain threshold). Both interventions were performed twice/week for 12 weeks. Walking capacity (maximal treadmill test), blood pressure (auscultatory), cardiac output (CO2 rebreathing), heart rate (ECG), stroke volume, systemic vascular resistance, forearm and calf vascular resistance (plethysmography), and low (LF) and high frequency (HF) components of heart rate variability and spontaneous baroreflex sensitivity were measured at baseline and after 12 weeks of the study.RESULTS: WT increased total walking distance (+302±85m, p=0.001) and spontaneous baroreflex sensitivity (+2.13±1.07ms/mmHg, p=0.02). Additionally, at rest, WT decreased systolic and mean blood pressures (-10±3 and -5±2mmHg, p=0.001 and p=0.01, respectively), cardiac output (-0.37±0.24l/min, p=0.03), heart rate (-4±2bpm, p=0.001), forearm vascular resistance (-8.5±2.8U, p=0.02) and LF/HF (-1.24±0.99, p=0.001). No change was observed in the CG.CONCLUSIONS: In addition to increasing walking capacity, WT improved cardiovascular function and autonomic regulation in patients with IC.
AB - OBJECTIVES: This study investigated the effects of walking training (WT) on cardiovascular function and autonomic regulation in patents with intermittent claudication (IC).DESIGN: Randomized controlled trial.METHODS: Forty-two male patients with IC (≥50years) were randomly allocated into two groups: control (CG, n=20, 30min of stretching exercises) and WT (WTG, n=22, 15 bouts of 2min of walking interpolated by 2min of upright rest-walking intensity was set at the heart rate of pain threshold). Both interventions were performed twice/week for 12 weeks. Walking capacity (maximal treadmill test), blood pressure (auscultatory), cardiac output (CO2 rebreathing), heart rate (ECG), stroke volume, systemic vascular resistance, forearm and calf vascular resistance (plethysmography), and low (LF) and high frequency (HF) components of heart rate variability and spontaneous baroreflex sensitivity were measured at baseline and after 12 weeks of the study.RESULTS: WT increased total walking distance (+302±85m, p=0.001) and spontaneous baroreflex sensitivity (+2.13±1.07ms/mmHg, p=0.02). Additionally, at rest, WT decreased systolic and mean blood pressures (-10±3 and -5±2mmHg, p=0.001 and p=0.01, respectively), cardiac output (-0.37±0.24l/min, p=0.03), heart rate (-4±2bpm, p=0.001), forearm vascular resistance (-8.5±2.8U, p=0.02) and LF/HF (-1.24±0.99, p=0.001). No change was observed in the CG.CONCLUSIONS: In addition to increasing walking capacity, WT improved cardiovascular function and autonomic regulation in patients with IC.
KW - Aged
KW - Blood Pressure
KW - Case-Control Studies
KW - Exercise Test/methods
KW - Exercise Therapy
KW - Heart Rate/physiology
KW - Humans
KW - Intermittent Claudication/physiopathology
KW - Male
KW - Middle Aged
KW - Oxygen Consumption/physiology
KW - Pain Threshold/physiology
KW - Stroke Volume/physiology
KW - Vascular Resistance/physiology
KW - Walking/physiology
U2 - 10.1016/j.jsams.2017.02.011
DO - 10.1016/j.jsams.2017.02.011
M3 - Article
C2 - 28389218
SN - 1440-2440
VL - 20
SP - 886
EP - 892
JO - Journal of Science and Medicine in Sport
JF - Journal of Science and Medicine in Sport
IS - 10
ER -