Wellcome Trust Centre for Mitochondrial Research

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Abstract

The Wellcome Trust Centre for Mitochondrial Research Group (MRG) based at Newcastle University has been doing pioneering research into mitochondrial abnormalities. They have recently achieved some breakthroughs in developing approaches that may be able to prevent people who carry mitochondrial disease from passing them on to their children. The MRG required a means of explaining the process of pronuclear transfer to educate and inform those who showed the potential to develop the disease. This involved understanding and translating the scientific knowledge and interpreting it into a more accessible means. Originally described as requiring a series of 2D still images, it quickly became apparent that a better direction of communicating this procedure was through a series of 3D animations. By selecting this approach the storyline of the technique became easier to grasp, allowing the viewer to follow without the need of requiring a scientific background. Building on the knowledge gained from an earlier animation for Bio Transformations, the challenge was to place the viewer in a larger than life situation, visualising features that were unknown to them, yet constructing them to be recognisable and familiar. The storyline altered over a series of meetings, sketch storyboards and wireframe animations from the complex scientific explanation. Throughout the series of meetings I employed an ‘artistic license’ to create a more theatrical feature, moving slightly away from the actual detailed science in order to tell the narrative in a more intelligible manner.
Original languageEnglish
Publication statusAccepted/In press - 2010

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