TY - JOUR
T1 - xQTL workbench
T2 - A scalable web environment for multi-level QTL analysis
AU - Arends, Danny
AU - van der Velde, K. Joeri
AU - Prins, Pjotr
AU - Broman, Karl W.
AU - Möller, Steffen
AU - Jansen, Ritsert C.
AU - Swertz, Morris A.
N1 - Funding Information:
Funding: National Institutes of Health (GM074244 to KB); Netherlands Organisation for Scientific Research (NWO)/TTI Green Genetics (1CC029RP to P.P.); NWO (Rubicon 825.09.008 to M.A.S), Centre for BioSystems Genomics (CBSG), Netherlands Consortium of Systems Biology (NCSB) (to D.A.), Netherlands Bioinformatics Center (NBIC) (to M.A.S.), all part of Netherlands Genomics Initiative/NWO; Target/LifeLines co-funded by the European Regional Development Fund and NWO (to M.A.S.); and EU-FP7 Projects PANACEA (222936 to K.J.v.d.v.) and EURATRANS (241504 to R.C.J.).
PY - 2012/4
Y1 - 2012/4
N2 - Summary: xQTL workbench is a scalable web platform for the mapping of quantitative trait loci (QTLs) at multiple levels: for example gene expression (eQTL), protein abundance (pQTL), metabolite abundance (mQTL) and phenotype (phQTL) data. Popular QTL mapping methods for model organism and human populations are accessible via the web user interface. Large calculations scale easily on to multi-core computers, clusters and Cloud. All data involved can be uploaded and queried online: markers, genotypes, microarrays, NGS, LC-MS, GC-MS, NMR, etc. When new data types come available, xQTL workbench is quickly customized using the Molgenis software generator.
AB - Summary: xQTL workbench is a scalable web platform for the mapping of quantitative trait loci (QTLs) at multiple levels: for example gene expression (eQTL), protein abundance (pQTL), metabolite abundance (mQTL) and phenotype (phQTL) data. Popular QTL mapping methods for model organism and human populations are accessible via the web user interface. Large calculations scale easily on to multi-core computers, clusters and Cloud. All data involved can be uploaded and queried online: markers, genotypes, microarrays, NGS, LC-MS, GC-MS, NMR, etc. When new data types come available, xQTL workbench is quickly customized using the Molgenis software generator.
UR - http://www.scopus.com/inward/record.url?scp=84859241218&partnerID=8YFLogxK
U2 - 10.1093/bioinformatics/bts049
DO - 10.1093/bioinformatics/bts049
M3 - Article
C2 - 22308096
AN - SCOPUS:84859241218
SN - 1367-4803
VL - 28
SP - 1042
EP - 1044
JO - Bioinformatics
JF - Bioinformatics
IS - 7
M1 - bts049
ER -