xQTL workbench: A scalable web environment for multi-level QTL analysis

Danny Arends, K. Joeri van der Velde, Pjotr Prins, Karl W. Broman, Steffen Möller, Ritsert C. Jansen, Morris A. Swertz*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Summary: xQTL workbench is a scalable web platform for the mapping of quantitative trait loci (QTLs) at multiple levels: for example gene expression (eQTL), protein abundance (pQTL), metabolite abundance (mQTL) and phenotype (phQTL) data. Popular QTL mapping methods for model organism and human populations are accessible via the web user interface. Large calculations scale easily on to multi-core computers, clusters and Cloud. All data involved can be uploaded and queried online: markers, genotypes, microarrays, NGS, LC-MS, GC-MS, NMR, etc. When new data types come available, xQTL workbench is quickly customized using the Molgenis software generator.

Original languageEnglish
Article numberbts049
Pages (from-to)1042-1044
Number of pages3
JournalBioinformatics
Volume28
Issue number7
DOIs
Publication statusPublished - Apr 2012
Externally publishedYes

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