Kay Padget

Effect of TDP2 on the Level of TOP2-DNA Complexes and SUMOylated TOP2-DNA Complexes

Lee, K. C., Swan, R. L., Sondka, Z., Padget, K., Cowell, I. G. & Austin, C. A., 14 Jul 2018, In: International Journal of Molecular Sciences. 19, 7, p. 2056-2071 15 p.

Research output: Contribution to journal › Article › peer-review

Genome-wide ChIP-seq analysis of human TOP2B occupancy in MCF7 breast cancer epithelial cells

Manville, C., Smith, K., Sondka, Z., Rance, H. A., Cockell, S., Cowell, I., Lee, K. C., Morris, N., Padget, K., Jackson, G. & Austin, C., Nov 2015, In: Biology Open. 4, 11, p. 1436-1447

Research output: Contribution to journal › Article › peer-review

Leptin up-regulates TLR2 in human monocytes

Jaedicke, K., Roythorne, A., Padget, K., Todryk, S., Preshaw, P. & Taylor, J., 22 Apr 2013, In: Journal of Leukocyte Biology. 93, 4, p. 561-571

Research output: Contribution to journal › Article › peer-review

Model for MLL translocations in therapy-related leukemia involving topoisomerase II -mediated DNA strand breaks and gene proximity

Cowell, I., Sondka, Z., Smith, K., Lee, K. C., Manville, C., Sidorczuk-Lesthuruge, M., Rance, H. A., Padget, K., Jackson, G., Adachi, N. & Austin, C., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 23, p. 8989-8994

Research output: Contribution to journal › Article › peer-review

MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA

Lee, K. C., Padget, K., Curtis, H., Cowell, I., Moiani, D., Sondka, Z., Morris, N., Jackson, G., Cockell, S., Tainer, J. & Austin, C., 2012, In: Biology Open. 1, 9, p. 863-873

Research output: Contribution to journal › Article › peer-review

Histone deacetylase inhibition redistributes topoisomerase IIb from heterochromatin to euchromatin

Cowell, I., Papageorgiou, N., Padget, K., Watters, G. & Austin, C., 2011, In: Nucleus. 2, 1, p. 61-71

Research output: Contribution to journal › Article › peer-review

Curcumin Induces High Levels of Topoisomerase I− and II−DNA Complexes in K562 Leukemia Cells

López-lázaro, M., Willmore, E., Jobson, A., Gilroy, K. L., Curtis, H., Padget, K. & Austin, C. A., Dec 2007, In: Journal of Natural Products. 70, 12, p. 1884-1888

Research output: Contribution to journal › Article › peer-review

mAMSA resistant human topoisomerase II  mutation G465D has reduced ATP hydrolysis activity

Gilroy, K. L., Leontiou, C., Padget, K., Lakey, J. & Austin, C., 1 Jan 2006, In: Nucleic Acids Research. 34, 5, p. 1597-1607

Research output: Contribution to journal › Article › peer-review

Deacetylase Activity Associates with Topoisomerase II and Is Necessary for Etoposide-induced Apoptosis

Johnson, C. A., Padget, K., Austin, C. A. & Turner, B. M., 16 Feb 2001, In: Journal of Biological Chemistry. 276, 7, p. 4539-4542

Research output: Contribution to journal › Article › peer-review

Quantitation of DNA topoisomerase IIα and β in human leukaemia cells by immunoblotting

Padget, K., Pearson, A. & Austin, C., 23 Oct 2000, In: Leukemia. 14, 11, p. 1997-2005

Research output: Contribution to journal › Article › peer-review