Meera Soundararajan
Senior Lecturer
Publications
- 2020
Novel 1‑hydroxypyridin‑2‑one metal chelators prevent and rescue ubiquitin proteasomal‑related neuronal injury in an in vitro model of Parkinson’s disease
Lewis, F., Farooz, S., Elson, J., Hubscher-Bruder, V., Brandel, J., Soundararajan, M., Smith, D., Dexter, D., Tetard, D. & Pienaar, I., Mar 2020, In : Archives of Toxicology. 94, 3, p. 813-831 19 p.Research output: Contribution to journal › Article
- 2019
Epidermal growth factor receptor (EGFR) gene alteration and protein overexpression in Malaysian triple-negative breast cancer (TNBC) cohort
Zakaria, Z., Zulkifle, M. F., Wan Hasan, W. A. N., Azhari, A. K., Abdul Raub, S. H., Eswaran, J., Soundararajan, M. & Syed Husain, S. N. A., 20 Sep 2019, In : OncoTargets and Therapy. 12, p. 7749-7756Research output: Contribution to journal › Article
Proteomics and bioinformatics analyses identify novel cellular roles outside mitochondrial function for human miro GTPases
Kay, L. J., Sangal, V., Black, G. W. & Soundararajan, M., 1 Jan 2019, In : Molecular and Cellular Biochemistry. 451, 1-2, p. 21-35 15 p.Research output: Contribution to journal › Article
- 2018
Human Miro Proteins Act as NTP Hydrolases through a Novel, Non-Canonical Catalytic Mechanism
Peters, D., Kay, L., Eswaran, J., Lakey, J. & Soundararajan, M., 2 Dec 2018, In : International Journal of Molecular Sciences. 19, 12, 3839.Research output: Contribution to journal › Article
Understanding Miro GTPases: Implications in the Treatment of Neurodegenerative Disorders
Kay, L., Pienaar, I. S., Cooray, R., Black, G. & Soundararajan, M., 1 Sep 2018, In : Molecular Neurobiology. 55, 9, p. 7352-7365 14 p.Research output: Contribution to journal › Review article
- 2016
Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A
Kay, L. J., Smulders-Srinivasan, T. & Soundararajan, M., 9 Aug 2016, Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods. Christov, C. (ed.). London: Elsevier, Vol. 105. p. 127-171Research output: Chapter in Book/Report/Conference proceeding › Chapter
Impact of the apoptotic regulator DRAK2 in chronic lymphocytic leukemia
Ciardullo, C., Zhou, P., Willmore, E., Harrison, C. J., Hall, A., Eswaran, J. & Soundararajan, M., 12 Apr 2016.Research output: Contribution to conference › Poster
- 2013
Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition
Soundararajan, M., Roos, A., Savitsky, P., Filippakopoulos, P., Kettenbach, A., Olsen, J., Gerber, S., Eswaran, J., Knapp, S. & Elkins, J., 2013, In : Structure. 21, 6, p. 986-996Research output: Contribution to journal › Article
- 2012
Atypical GTPases as drug targets
Soundararajan, M. & Eswaran, J., 2012, In : Anti-Cancer Agents in Medicinal Chemistry. 12, 1, p. 19-28Research output: Contribution to journal › Article
- 2011
Leucettines, a Class of Potent Inhibitors of cdc2-Like Kinases and Dual Specificity, Tyrosine Phosphorylation Regulated Kinases Derived from the Marine Sponge Leucettamine B: Modulation of Alternative Pre-RNA Splicing
Debdab, M., Carreaux, F., Renault, S., Soundararajan, M., Fedorov, O., Filippakopoulos, P., Lozach, O., Babault, L., Tahtouh, T., Baratte, B., Ogawa, Y., Hagiwara, M., Eisenreich, A., Rauch, U., Knapp, S., Meijer, L. & Bazureau, J-P., 26 May 2011, In : Journal of Medicinal Chemistry. 54, 12, p. 4172-4186Research output: Contribution to journal › Article